Abstract
A recent publication in this journal reported the application of a targeted proteomic strategy using a quantitative concatemer (QconCAT) standard to the assessment of allele-specific expression of UGT2B15 claiming this methodology to be a “novel” approach (J. Proteome Res. 2018, 17 (10), 3606−3612, DOI:10.1021/acs.jproteome.8b00620). While the application is not common, the method was previously described and reported by our group in relation to the quantification of CYP2B6 alleles (J. Proteome Res. 2013, 12 (12), 5934−5942, DOI: 10.1021/pr400279u) to assess the expression of a prevalent polymorphism in a Caucasian population.
Original language | English |
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Pages (from-to) | 574-574 |
Journal | J. Proteome Res. |
Volume | 18 |
Issue number | 1 |
Early online date | 16 Nov 2018 |
DOIs | |
Publication status | Published - 4 Jan 2019 |
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Biological Mass Spectrometry (BioMS) Facility
Knight, D. (Platform Lead), Warwood, S. (Senior Technical Specialist), Selley, J. (Technical Specialist), Taylor, G. (Technical Specialist), Fullwood, P. (Technical Specialist), Keevill, E.-J. (Senior Technician) & Allsey, J. (Technician)
FBMH Platform Sciences, Enabling Technologies & InfrastructureFacility/equipment: Facility