Results from First-in-Human Phase i Dose-Escalation Study of a Novel Bicycle Toxin Conjugate Targeting EphA2 (BT5528) in Patients with Advanced Solid Tumors

Babar  Bashir; Judy S.  Wang; Gerald  Falchook; Elisa  Fontana; Hendrik-Tobias  Arkenau; Louise Carter; Rachel  Galot; Bristi Basu; Alastair  Greystoke; Vivek  Subbiah; Debra L.  Richardson; Hanna Orr; Gavin  Bennett; Rajiv  Sharma; Hongmei  Xu; Paola  Paganoni; Cong  Xu; Carly  Campbell; Meredith  McKean

doi:10.1200/JCO.23.01107

Results from First-in-Human Phase i Dose-Escalation Study of a Novel Bicycle Toxin Conjugate Targeting EphA2 (BT5528) in Patients with Advanced Solid Tumors

Babar Bashir, Judy S. Wang, Gerald Falchook, Elisa Fontana, Hendrik-Tobias Arkenau, Louise Carter, Rachel Galot, Bristi Basu, Alastair Greystoke, Vivek Subbiah, Debra L. Richardson, Hanna Orr, Gavin Bennett, Rajiv Sharma, Hongmei Xu, Paola Paganoni, Cong Xu, Carly Campbell, Meredith McKean

Division of Cancer Sciences (L5)

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	3443-3452
Journal	Journal of Clinical Oncology
Volume	42
DOIs	https://doi.org/10.1200/JCO.23.01107
Publication status	Published - 10 Oct 2024

Research Beacons, Institutes and Platforms

Cancer

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1200/JCO.23.01107

Cite this

Bashir, B., Wang, J. S., Falchook, G., Fontana, E., Arkenau, H.-T., Carter, L., Galot, R., Basu, B., Greystoke, A., Subbiah, V., Richardson, D. L., Orr, H., Bennett, G., Sharma, R., Xu, H., Paganoni, P., Xu, C., Campbell, C., & McKean, M. (2024). Results from First-in-Human Phase i Dose-Escalation Study of a Novel Bicycle Toxin Conjugate Targeting EphA2 (BT5528) in Patients with Advanced Solid Tumors. Journal of Clinical Oncology, 42, 3443-3452. https://doi.org/10.1200/JCO.23.01107

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title = "Results from First-in-Human Phase i Dose-Escalation Study of a Novel Bicycle Toxin Conjugate Targeting EphA2 (BT5528) in Patients with Advanced Solid Tumors",

author = "Babar Bashir and Wang, {Judy S.} and Gerald Falchook and Elisa Fontana and Hendrik-Tobias Arkenau and Louise Carter and Rachel Galot and Bristi Basu and Alastair Greystoke and Vivek Subbiah and Richardson, {Debra L.} and Hanna Orr and Gavin Bennett and Rajiv Sharma and Hongmei Xu and Paola Paganoni and Cong Xu and Carly Campbell and Meredith McKean",

year = "2024",

month = oct,

day = "10",

doi = "10.1200/JCO.23.01107",

language = "English",

volume = "42",

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journal = "Journal of Clinical Oncology",

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Bashir, B, Wang, JS, Falchook, G, Fontana, E, Arkenau, H-T, Carter, L, Galot, R, Basu, B, Greystoke, A, Subbiah, V, Richardson, DL, Orr, H, Bennett, G, Sharma, R, Xu, H, Paganoni, P, Xu, C, Campbell, C & McKean, M 2024, 'Results from First-in-Human Phase i Dose-Escalation Study of a Novel Bicycle Toxin Conjugate Targeting EphA2 (BT5528) in Patients with Advanced Solid Tumors', Journal of Clinical Oncology, vol. 42, pp. 3443-3452. https://doi.org/10.1200/JCO.23.01107

TY - JOUR

T1 - Results from First-in-Human Phase i Dose-Escalation Study of a Novel Bicycle Toxin Conjugate Targeting EphA2 (BT5528) in Patients with Advanced Solid Tumors

AU - Bashir, Babar

AU - Wang, Judy S.

AU - Falchook, Gerald

AU - Fontana, Elisa

AU - Arkenau, Hendrik-Tobias

AU - Carter, Louise

AU - Galot, Rachel

AU - Basu, Bristi

AU - Greystoke, Alastair

AU - Subbiah, Vivek

AU - Richardson, Debra L.

AU - Orr, Hanna

AU - Bennett, Gavin

AU - Sharma, Rajiv

AU - Xu, Hongmei

AU - Paganoni, Paola

AU - Xu, Cong

AU - Campbell, Carly

AU - McKean, Meredith

PY - 2024/10/10

Y1 - 2024/10/10

U2 - 10.1200/JCO.23.01107

DO - 10.1200/JCO.23.01107

M3 - Article

SN - 0732-183X

VL - 42

SP - 3443

EP - 3452

JO - Journal of Clinical Oncology

JF - Journal of Clinical Oncology

ER -