Retooling microorganisms for the fermentative production of alcohols

Helen Toogood; Nigel Scrutton

doi:10.1016/j.copbio.2017.08.010

Retooling microorganisms for the fermentative production of alcohols

Research output: Contribution to journal › Article › peer-review

Abstract

Bioengineering and synthetic biology approaches have revolutionised the field of biotechnology, enabling the introduction of non-native and de novo pathways for biofuels production. This ‘retooling’ of microorganisms is also applied to the utilisation of mixed carbon components derived from lignocellulosic biomass, a major technical barrier for the development of economically viable fermentations. This review will discuss recent advances in microorganism engineering for efficient production of alcohols from waste biomass. These advances span the introduction of new pathways to alcohols, host modifications for more cost-effective utilisation of lignocellulosic waste and modifications of existing pathways for generating new fuel additives.

Original language	English
Journal	Current Opinion in Biotechnology
Volume	50
Early online date	6 Sept 2017
DOIs	https://doi.org/10.1016/j.copbio.2017.08.010
Publication status	Published - Apr 2018

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Manchester Institute of Biotechnology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.copbio.2017.08.010Licence: CC BY

Manchester Synthetic Biology Research Centre for Fine and Speciality Chemicals
Scrutton, N. (PI), Azapagic, A. (CoI), Balmer, A. (CoI), Barran, P. (CoI), Breitling, R. (CoI), Delneri, D. (CoI), Dixon, N. (CoI), Faulon, J.-L. (CoI), Flitsch, S. (CoI), Goble, C. (CoI), Goodacre, R. (CoI), Hay, S. (CoI), Kell, D. (CoI), Leys, D. (CoI), Lloyd, J. (CoI), Lockyer, N. (CoI), Martin, P. (CoI), Micklefield, J. (CoI), Munro, A. (CoI), Pedrosa Mendes, P. (CoI), Randles, S. (CoI), Salehi Yazdi, F. (CoI), Shapira, P. (CoI), Takano, E. (CoI), Turner, N. (CoI) & Winterburn, J. (CoI)
14/11/14 → 13/05/20
Project: Research

Cite this

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VL - 50

JO - Current Opinion in Biotechnology

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ER -

Retooling microorganisms for the fermentative production of alcohols

Abstract

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UN SDGs

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Manchester Synthetic Biology Research Centre for Fine and Speciality Chemicals

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