Rheumatoid cachexia and cardiovascular disease.

G S Metsios, A Stavropoulos-Kalinoglou, V F Panoulas, A Sandoo, T E Toms, A M Nevill, Y Koutedakis, G D Kitas

    Research output: Contribution to journalArticlepeer-review


    OBJECTIVE: It has been frequently stated that rheumatoid cachexia (RC) associates with increased cardiovascular risk; however, no studies to date have investigated this. The aim of this study was to investigate the association of RC with multiple novel and classical cardiovascular disease (CVD) risk factors and the presence of established CVD in rheumatoid arthritis (RA). METHODS: A total of 34 RA patients with RC (RA+RC) were identified from a database of 400 RA patients using published RC criteria and compared to the remaining patients (RA-RC) who did not fulfil RC criteria. All patients were assessed for fat and fat-free mass, albumin (indicator of catabolism), disease activity/severity, novel and classical risk CVD factors and established CVD. RESULTS: Fat-free mass (kg) and albumin (g/L) were significantly decreased in RA+RC vs. RA-RC patients: 37.3(33.9-41.6) vs. 45.9(41.2-55.5), p
    Original languageEnglish
    Pages (from-to)985-988
    JournalClinical and Experimental Rheumatology
    Issue number6
    Publication statusPublished - 2009


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