Rheumatoid cachexia and cardiovascular disease.

G S Metsios; A Stavropoulos-Kalinoglou; V F Panoulas; A Sandoo; T E Toms; A M Nevill; Y Koutedakis; G D Kitas

Rheumatoid cachexia and cardiovascular disease.

G S Metsios, A Stavropoulos-Kalinoglou, V F Panoulas, A Sandoo, T E Toms, A M Nevill, Y Koutedakis, G D Kitas

Research output: Contribution to journal › Article › peer-review

Abstract

OBJECTIVE: It has been frequently stated that rheumatoid cachexia (RC) associates with increased cardiovascular risk; however, no studies to date have investigated this. The aim of this study was to investigate the association of RC with multiple novel and classical cardiovascular disease (CVD) risk factors and the presence of established CVD in rheumatoid arthritis (RA). METHODS: A total of 34 RA patients with RC (RA+RC) were identified from a database of 400 RA patients using published RC criteria and compared to the remaining patients (RA-RC) who did not fulfil RC criteria. All patients were assessed for fat and fat-free mass, albumin (indicator of catabolism), disease activity/severity, novel and classical risk CVD factors and established CVD. RESULTS: Fat-free mass (kg) and albumin (g/L) were significantly decreased in RA+RC vs. RA-RC patients: 37.3(33.9-41.6) vs. 45.9(41.2-55.5), p

Original language	English
Pages (from-to)	985-988
Journal	Clinical and Experimental Rheumatology
Volume	27
Issue number	6
Publication status	Published - 2009

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title = "Rheumatoid cachexia and cardiovascular disease.",

abstract = "OBJECTIVE: It has been frequently stated that rheumatoid cachexia (RC) associates with increased cardiovascular risk; however, no studies to date have investigated this. The aim of this study was to investigate the association of RC with multiple novel and classical cardiovascular disease (CVD) risk factors and the presence of established CVD in rheumatoid arthritis (RA). METHODS: A total of 34 RA patients with RC (RA+RC) were identified from a database of 400 RA patients using published RC criteria and compared to the remaining patients (RA-RC) who did not fulfil RC criteria. All patients were assessed for fat and fat-free mass, albumin (indicator of catabolism), disease activity/severity, novel and classical risk CVD factors and established CVD. RESULTS: Fat-free mass (kg) and albumin (g/L) were significantly decreased in RA+RC vs. RA-RC patients: 37.3(33.9-41.6) vs. 45.9(41.2-55.5), p",

author = "Metsios, {G S} and A Stavropoulos-Kalinoglou and Panoulas, {V F} and A Sandoo and Toms, {T E} and Nevill, {A M} and Y Koutedakis and Kitas, {G D}",

year = "2009",

language = "English",

volume = "27",

pages = "985--988",

journal = "Clinical and Experimental Rheumatology",

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TY - JOUR

T1 - Rheumatoid cachexia and cardiovascular disease.

AU - Metsios, G S

AU - Stavropoulos-Kalinoglou, A

AU - Panoulas, V F

AU - Sandoo, A

AU - Toms, T E

AU - Nevill, A M

AU - Koutedakis, Y

AU - Kitas, G D

PY - 2009

Y1 - 2009

N2 - OBJECTIVE: It has been frequently stated that rheumatoid cachexia (RC) associates with increased cardiovascular risk; however, no studies to date have investigated this. The aim of this study was to investigate the association of RC with multiple novel and classical cardiovascular disease (CVD) risk factors and the presence of established CVD in rheumatoid arthritis (RA). METHODS: A total of 34 RA patients with RC (RA+RC) were identified from a database of 400 RA patients using published RC criteria and compared to the remaining patients (RA-RC) who did not fulfil RC criteria. All patients were assessed for fat and fat-free mass, albumin (indicator of catabolism), disease activity/severity, novel and classical risk CVD factors and established CVD. RESULTS: Fat-free mass (kg) and albumin (g/L) were significantly decreased in RA+RC vs. RA-RC patients: 37.3(33.9-41.6) vs. 45.9(41.2-55.5), p

AB - OBJECTIVE: It has been frequently stated that rheumatoid cachexia (RC) associates with increased cardiovascular risk; however, no studies to date have investigated this. The aim of this study was to investigate the association of RC with multiple novel and classical cardiovascular disease (CVD) risk factors and the presence of established CVD in rheumatoid arthritis (RA). METHODS: A total of 34 RA patients with RC (RA+RC) were identified from a database of 400 RA patients using published RC criteria and compared to the remaining patients (RA-RC) who did not fulfil RC criteria. All patients were assessed for fat and fat-free mass, albumin (indicator of catabolism), disease activity/severity, novel and classical risk CVD factors and established CVD. RESULTS: Fat-free mass (kg) and albumin (g/L) were significantly decreased in RA+RC vs. RA-RC patients: 37.3(33.9-41.6) vs. 45.9(41.2-55.5), p

M3 - Article

C2 - 20149317

SN - 1593-098X

VL - 27

SP - 985

EP - 988

JO - Clinical and Experimental Rheumatology

JF - Clinical and Experimental Rheumatology

IS - 6

ER -

Rheumatoid cachexia and cardiovascular disease.

Abstract

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