TY - JOUR
T1 - Robust genetic circuit design
T2 - A mixed H∞ and IQC analysis
AU - Chen, Ruijuan
AU - Pan, Wei
AU - Fu, Dongfei
AU - He, Xin
N1 - Publisher Copyright:
© 2017 Ruijuan Chen et al.
PY - 2017/4/6
Y1 - 2017/4/6
N2 - This paper considers the problem of designing a genetic circuit which is robust to noise effect. To achieve this goal, a mixed H∞ and Integral Quadratic Constraints (IQC) approach is proposed. In order to minimize the effects of external noise on the genetic regulatory network in terms of H∞ norm, a design procedure of Hill coefficients in the promoters is presented. The IQC approach is introduced to analyze and guarantee the stability of the designed circuit.
AB - This paper considers the problem of designing a genetic circuit which is robust to noise effect. To achieve this goal, a mixed H∞ and Integral Quadratic Constraints (IQC) approach is proposed. In order to minimize the effects of external noise on the genetic regulatory network in terms of H∞ norm, a design procedure of Hill coefficients in the promoters is presented. The IQC approach is introduced to analyze and guarantee the stability of the designed circuit.
UR - http://www.scopus.com/inward/record.url?scp=85018841159&partnerID=8YFLogxK
U2 - 10.1155/2017/5757943
DO - 10.1155/2017/5757943
M3 - Article
AN - SCOPUS:85018841159
SN - 1687-9120
VL - 2017
SP - 1
EP - 6
JO - Advances in Mathematical Physics
JF - Advances in Mathematical Physics
M1 - 5757943
ER -