Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 326-333 |
| Number of pages | 8 |
| Journal | Respiratory Investigation |
| Volume | 55 |
| Issue number | 6 |
| Early online date | 22 Sept 2017 |
| DOIs | |
| Publication status | Published - 2017 |
Keywords
- Airway inflammation
- Lung
- Lung function
- Obstructive sleep apnea
- Sleep
- inducible nitric oxide synthase
- intercellular adhesion molecule 1
- interleukin 6
- interleukin 8
- tumor necrosis factor
- apnea hypopnea index
- bronchoalveolar lavage fluid
- chronic obstructive lung disease
- disease association
- disease exacerbation
- disease severity
- forced vital capacity
- functional residual capacity
- human
- lung volume
- nonhuman
- oxidative stress
- positive end expiratory pressure
- protein expression
- respiratory tract inflammation
- Review
- sleep disordered breathing
- body mass
- complication
- hypoxia
- inflammation
- lung
- obesity
- pathophysiology
- physiology
- respiratory tract disease
- sleep deprivation
- total lung capacity
- vibration
- Body Mass Index
- Continuous Positive Airway Pressure
- Humans
- Hypoxia
- Inflammation
- Obesity
- Oxidative Stress
- Respiratory Tract Diseases
- Sleep Apnea, Obstructive
- Sleep Deprivation
- Total Lung Capacity
- Vibration
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In: Respiratory Investigation, Vol. 55, No. 6, 2017, p. 326-333.
Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - Role of lung volume and airway inflammation in obstructive sleep apnea
AU - Bikov, A.
AU - Losonczy, G.
AU - Kunos, L.
N1 - Export Date: 31 October 2018 Correspondence Address: Bikov, A.; Department of Pulmonology, Semmelweis University, 1/C Dios arok, Hungary; email: [email protected] Chemicals/CAS: inducible nitric oxide synthase, 501433-35-8; intercellular adhesion molecule 1, 126547-89-5; interleukin 8, 114308-91-7 Funding details: MTA, Magyar Tudományos Akadémia Funding text: This publication was supported by the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences granted to Andras Bikov. References: American Academy of Sleep Medicine, The international classification of sleep disorders (2014), 3rd edition AASM Resource Library Darien, IL, USA; Gislason, T., Sunnergren, O., Obstructive sleep apnoea in adults (2014) European respiratory monograph. Respiratory epidemiology, pp. 88-105. , I. Annesi-Maesano G. Viegi B. 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PY - 2017
Y1 - 2017
N2 - Obstructive sleep apnea (OSA) is a prevalent disorder that affects not only the upper airways but also the intrathoracic airways. In this review, we summarize the results of studies on lung function and airway inflammation. We provide evidence that the alterations in intrathoracic airways observed in OSA are not purely consequences of mechanical trauma and oxidative stress during apneic events but have a causal role in the structural changes associated with OSA and increasing severity of this disorder. © 2017 The Japanese Respiratory Society
AB - Obstructive sleep apnea (OSA) is a prevalent disorder that affects not only the upper airways but also the intrathoracic airways. In this review, we summarize the results of studies on lung function and airway inflammation. We provide evidence that the alterations in intrathoracic airways observed in OSA are not purely consequences of mechanical trauma and oxidative stress during apneic events but have a causal role in the structural changes associated with OSA and increasing severity of this disorder. © 2017 The Japanese Respiratory Society
KW - Airway inflammation
KW - Lung
KW - Lung function
KW - Obstructive sleep apnea
KW - Sleep
KW - inducible nitric oxide synthase
KW - intercellular adhesion molecule 1
KW - interleukin 6
KW - interleukin 8
KW - tumor necrosis factor
KW - apnea hypopnea index
KW - bronchoalveolar lavage fluid
KW - chronic obstructive lung disease
KW - disease association
KW - disease exacerbation
KW - disease severity
KW - forced vital capacity
KW - functional residual capacity
KW - human
KW - lung volume
KW - nonhuman
KW - oxidative stress
KW - positive end expiratory pressure
KW - protein expression
KW - respiratory tract inflammation
KW - Review
KW - sleep disordered breathing
KW - body mass
KW - complication
KW - hypoxia
KW - inflammation
KW - lung
KW - obesity
KW - pathophysiology
KW - physiology
KW - respiratory tract disease
KW - sleep deprivation
KW - total lung capacity
KW - vibration
KW - Body Mass Index
KW - Continuous Positive Airway Pressure
KW - Humans
KW - Hypoxia
KW - Inflammation
KW - Obesity
KW - Oxidative Stress
KW - Respiratory Tract Diseases
KW - Sleep Apnea, Obstructive
KW - Sleep Deprivation
KW - Total Lung Capacity
KW - Vibration
U2 - 10.1016/j.resinv.2017.08.009
DO - 10.1016/j.resinv.2017.08.009
M3 - Article
SN - 2212-5345
VL - 55
SP - 326
EP - 333
JO - Respiratory Investigation
JF - Respiratory Investigation
IS - 6
ER -