Ruthenium Catalyzed meta-Carboxylation

Helen Barlow; Christopher Teskey; Michael Greaney

doi:10.1021/acs.orglett.7b03387

Ruthenium Catalyzed meta-Carboxylation

Helen Barlow, Christopher Teskey, Michael Greaney

Research output: Contribution to journal › Article › peer-review

Abstract

The meta-carboxylation of arenes containing pyridine and other azine directing groups is reported. Using carbon tetrabromide as the C1 source, ruthenium(III) trichloride catalysis enables functionalization of the arene meta C-H position, affording carboxy methyl ester products after in situ reaction with methanol.

Original language	English
Journal	Organic Letters
Early online date	23 Nov 2017
DOIs	https://doi.org/10.1021/acs.orglett.7b03387
Publication status	Published - 2017

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10.1021/acs.orglett.7b03387Licence: CC BY

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title = "Ruthenium Catalyzed meta-Carboxylation",

abstract = "The meta-carboxylation of arenes containing pyridine and other azine directing groups is reported. Using carbon tetrabromide as the C1 source, ruthenium(III) trichloride catalysis enables functionalization of the arene meta C-H position, affording carboxy methyl ester products after in situ reaction with methanol.",

author = "Helen Barlow and Christopher Teskey and Michael Greaney",

year = "2017",

doi = "10.1021/acs.orglett.7b03387",

language = "English",

journal = "Organic Letters",

issn = "1523-7052",

publisher = "American Chemical Society",

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AU - Barlow, Helen

AU - Teskey, Christopher

AU - Greaney, Michael

PY - 2017

Y1 - 2017

N2 - The meta-carboxylation of arenes containing pyridine and other azine directing groups is reported. Using carbon tetrabromide as the C1 source, ruthenium(III) trichloride catalysis enables functionalization of the arene meta C-H position, affording carboxy methyl ester products after in situ reaction with methanol.

AB - The meta-carboxylation of arenes containing pyridine and other azine directing groups is reported. Using carbon tetrabromide as the C1 source, ruthenium(III) trichloride catalysis enables functionalization of the arene meta C-H position, affording carboxy methyl ester products after in situ reaction with methanol.

U2 - 10.1021/acs.orglett.7b03387

DO - 10.1021/acs.orglett.7b03387

M3 - Article

SN - 1523-7052

JO - Organic Letters

JF - Organic Letters

ER -

Ruthenium Catalyzed meta-Carboxylation

Abstract

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