Safety Assessment of Graphene-Based Materials: Focus on Human Health and the Environment

Bengt Fadeel, Cyrill Bussy, Sonia Merino, Ester Vázquez, Emmanuel Flahaut, Florence Mouchet, Lauris Evariste, Laury Gauthier, Antti J Koivisto, Ulla Vogel, Cristina Martin, Lucia G Delogu, Tina Bürki-Thurnherr, Peter Wick, Didier Beloin-Saint-Pierre, Roland Hischier, Marco Pelin, Fabio Candotto Carniel, Mauro Tretiach, Fabrizia CescaFabio Benfenati, Denis Scaini, Laura Ballerini, Kostas Kostarelos, Maurizio Prato, Alberto Bianco

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Graphene and its derivatives are heralded as 'miracle' materials with manifold applications in different sectors of society from electronics to energy storage to medicine. The increasing exploitation of graphene-based materials (GBMs) necessitates a comprehensive evaluation of the potential impact of these materials on human health and the environment. Here we discuss synthesis and characterization of GBMs as well as human and environmental hazard assessment of GBMs using in vitro and in vivo model systems with the aim to understand the properties that underlie the biological effects of these materials; not all GBMs are alike, and it is essential that we disentangle the structure-activity relationships for this class of materials.

Original languageEnglish
JournalACS Nano
Early online date2 Nov 2018
Publication statusPublished - 2018


  • Graphene
  • Safety assessment
  • Health
  • Environment effects
  • 2D materials
  • Characterisation
  • Life cycle assessment (LCA)
  • Exposure assessment
  • Hazard and risk assessment
  • Nanomaterials
  • Nanotoxicology

Research Beacons, Institutes and Platforms

  • Advanced materials
  • Advanced Materials in Medicine
  • Lydia Becker Institute
  • National Graphene Institute
  • Manchester Environmental Research Institute


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