Sarcomas in North West England: I. Histopathological peer review

Anthony Freemont, M. Harris, A. L. Hartley, V. Blair, J. M. Birch, S. S. Banerjee, A. J J Freemont McClure, L. J. McWilliam

    Research output: Contribution to journalArticlepeer-review


    A total of 468 cases of bone soft tissue and visceral sarcomas (and certain other tumours) diagnosed during the years 1982-84 in North West England were entered in a study of histopathological peer review, incidence and survival. This paper describes the effects of peer review. Material was reviewed by a panel of five pathologists for 413 of the 450 cases originally registered as sarcomas with the Regional Cancer Registry. The diagnosis of sarcomas was confirmed in 76% cases and and there was agreement on sub-type for 53% cases. Measures of agreement were lowest for the two sub-types most commonly diagnosed i.e. malignant fibrous histiocytoma and leiomyosarcoma. Degree of agreement between individual pathologists and final panel diagnosis was also very variable but never less than 65%. It is concluded that second opinion is essential in cases of presumed sarcomas for studies of incidence and aetiology and to ensure that appropriate treatment is selected.
    Original languageEnglish
    Pages (from-to)315-320
    Number of pages5
    JournalBritish Journal of Cancer
    Issue number2
    Publication statusPublished - 1991


    • diagnosis: Bone Neoplasms
    • England
    • Humans
    • Peer Review
    • Research Support, Non-U.S. Gov't
    • classification: Sarcoma
    • diagnosis: Soft Tissue Neoplasms


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