Sarcopenia and its relationship with bone mineral density in middle-aged and elderly European men

S. Verschueren; E. Gielen; T. W. O'Neill; S. R. Pye; J. E. Adams; K. A. Ward; F. C. Wu; P. Szulc; M. Laurent; F. Claessens; D. Vanderschueren; S. Boonen

doi:10.1007/s00198-012-2057-z

Sarcopenia and its relationship with bone mineral density in middle-aged and elderly European men

S. Verschueren, E. Gielen, T. W. O'Neill, S. R. Pye, J. E. Adams, K. A. Ward, F. C. Wu, P. Szulc, M. Laurent, F. Claessens, D. Vanderschueren, S. Boonen

Research output: Contribution to journal › Article › peer-review

Abstract

The aim of this study was to determine the relationship between reduced muscle mass (sarcopenia) and areal bone mineral density (BMDa) in middle-aged and elderly community-dwelling European men. Men with sarcopenia had significantly lower BMDa and were more likely to have osteoporosis compared with men without sarcopenia. Introduction: In men, the relationship between reduced muscle mass (sarcopenia) and BMDa is unclear. This study aimed to determine this relationship in middle-aged and elderly community-dwelling men. Methods: Men aged 40-79 years from the Manchester (UK) and Leuven (Belgium) cohorts of the European Male Ageing Study were invited to attend for assessment including dual-energy X-ray absorptiometry, from which appendicular lean mass (aLM), fat mass (FM) and whole-body, spine and hip BMDa were determined. Relative appendicular skeletal muscle mass (RASM) was calculated as aLM/height2. Muscle strength was assessed in subjects from Leuven. Sarcopenia was defined by RASM at

Original language	English
Pages (from-to)	87-98
Number of pages	11
Journal	Osteoporosis International
Volume	24
Issue number	1
DOIs	https://doi.org/10.1007/s00198-012-2057-z
Publication status	Published - Jan 2013

Keywords

Areal bone mineral density (BMDa)
Lean mass
Muscle strength
Osteoporosis
Relative appendicular skeletal muscle mass (RASM), sarcopenia

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10.1007/s00198-012-2057-z

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title = "Sarcopenia and its relationship with bone mineral density in middle-aged and elderly European men",

abstract = "The aim of this study was to determine the relationship between reduced muscle mass (sarcopenia) and areal bone mineral density (BMDa) in middle-aged and elderly community-dwelling European men. Men with sarcopenia had significantly lower BMDa and were more likely to have osteoporosis compared with men without sarcopenia. Introduction: In men, the relationship between reduced muscle mass (sarcopenia) and BMDa is unclear. This study aimed to determine this relationship in middle-aged and elderly community-dwelling men. Methods: Men aged 40-79 years from the Manchester (UK) and Leuven (Belgium) cohorts of the European Male Ageing Study were invited to attend for assessment including dual-energy X-ray absorptiometry, from which appendicular lean mass (aLM), fat mass (FM) and whole-body, spine and hip BMDa were determined. Relative appendicular skeletal muscle mass (RASM) was calculated as aLM/height2. Muscle strength was assessed in subjects from Leuven. Sarcopenia was defined by RASM at",

keywords = "Areal bone mineral density (BMDa), Lean mass, Muscle strength, Osteoporosis, Relative appendicular skeletal muscle mass (RASM), sarcopenia",

author = "S. Verschueren and E. Gielen and O'Neill, {T. W.} and Pye, {S. R.} and Adams, {J. E.} and Ward, {K. A.} and Wu, {F. C.} and P. Szulc and M. Laurent and F. Claessens and D. Vanderschueren and S. Boonen",

year = "2013",

month = jan,

doi = "10.1007/s00198-012-2057-z",

language = "English",

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T1 - Sarcopenia and its relationship with bone mineral density in middle-aged and elderly European men

AU - Verschueren, S.

AU - Gielen, E.

AU - O'Neill, T. W.

AU - Pye, S. R.

AU - Adams, J. E.

AU - Ward, K. A.

AU - Wu, F. C.

AU - Szulc, P.

AU - Laurent, M.

AU - Claessens, F.

AU - Vanderschueren, D.

AU - Boonen, S.

PY - 2013/1

Y1 - 2013/1

N2 - The aim of this study was to determine the relationship between reduced muscle mass (sarcopenia) and areal bone mineral density (BMDa) in middle-aged and elderly community-dwelling European men. Men with sarcopenia had significantly lower BMDa and were more likely to have osteoporosis compared with men without sarcopenia. Introduction: In men, the relationship between reduced muscle mass (sarcopenia) and BMDa is unclear. This study aimed to determine this relationship in middle-aged and elderly community-dwelling men. Methods: Men aged 40-79 years from the Manchester (UK) and Leuven (Belgium) cohorts of the European Male Ageing Study were invited to attend for assessment including dual-energy X-ray absorptiometry, from which appendicular lean mass (aLM), fat mass (FM) and whole-body, spine and hip BMDa were determined. Relative appendicular skeletal muscle mass (RASM) was calculated as aLM/height2. Muscle strength was assessed in subjects from Leuven. Sarcopenia was defined by RASM at

AB - The aim of this study was to determine the relationship between reduced muscle mass (sarcopenia) and areal bone mineral density (BMDa) in middle-aged and elderly community-dwelling European men. Men with sarcopenia had significantly lower BMDa and were more likely to have osteoporosis compared with men without sarcopenia. Introduction: In men, the relationship between reduced muscle mass (sarcopenia) and BMDa is unclear. This study aimed to determine this relationship in middle-aged and elderly community-dwelling men. Methods: Men aged 40-79 years from the Manchester (UK) and Leuven (Belgium) cohorts of the European Male Ageing Study were invited to attend for assessment including dual-energy X-ray absorptiometry, from which appendicular lean mass (aLM), fat mass (FM) and whole-body, spine and hip BMDa were determined. Relative appendicular skeletal muscle mass (RASM) was calculated as aLM/height2. Muscle strength was assessed in subjects from Leuven. Sarcopenia was defined by RASM at

KW - Areal bone mineral density (BMDa)

KW - Lean mass

KW - Muscle strength

KW - Osteoporosis

KW - Relative appendicular skeletal muscle mass (RASM), sarcopenia

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DO - 10.1007/s00198-012-2057-z

M3 - Article

C2 - 22776861

SN - 1433-2965

VL - 24

SP - 87

EP - 98

JO - Osteoporosis International

JF - Osteoporosis International

IS - 1

ER -

Sarcopenia and its relationship with bone mineral density in middle-aged and elderly European men

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Keywords

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