Screening for ovarian cancer.

Usha Menon, Ian Jacobs

    Research output: Contribution to journalArticlepeer-review

    Abstract

    There has been considerable interest in the prospect of early detection of ovarian cancer through screening asymptomatic women, in both the general and 'high-risk' populations. Over the last decade screening strategies using the serum marker CA126 and transvaginal ultrasound have been refined and encouraging data have emerged on the impact of screening on ovarian cancer survival rates. Two randomized controlled trials are now underway in the general population to establish the impact of screening on ovarian cancer mortality while comprehensively tackling the issues of compliance, health economics and physical and psychological morbidity. In addition, trials in the high-risk population aimed at optimizing the current strategy have commenced in both the USA and the UK.
    Original languageEnglish
    JournalBest practice & research. Clinical obstetrics & gynaecology
    Volume16
    Issue number4
    Publication statusPublished - Aug 2002

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