Selective synthesis of double temperature-sensitive polymer-peptide conjugates

Florentina Stoica; Cameron Alexander; Nicola Tirelli; Aline F. Miller; Alberto Saiani; Aline Saiani

doi:10.1039/b806782a

Selective synthesis of double temperature-sensitive polymer-peptide conjugates

Florentina Stoica, Cameron Alexander, Nicola Tirelli, Aline F. Miller, Alberto Saiani, Aline Saiani

Research output: Contribution to journal › Article › peer-review

Abstract

A novel synthetic route has been developed to couple selectively a modified octa-peptide, that is able to gel at low temperature, to the prototypical thermoresponsive polymer poly(N-isopropylacrylamide) to give a bioconjugate that exhibits double thermoresponsiveness. © The Royal Society of Chemistry.

Original language	English
Pages (from-to)	4433-4435
Number of pages	2
Journal	Chemical Communications
Issue number	37
DOIs	https://doi.org/10.1039/b806782a
Publication status	Published - 2008

Keywords

chemistry: Acrylamides
Calorimetry, Differential Scanning
chemistry: Peptides
chemistry: Polymers
Temperature

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10.1039/b806782a

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@article{1807c55e749446279140e9212f679459,

title = "Selective synthesis of double temperature-sensitive polymer-peptide conjugates",

abstract = "A novel synthetic route has been developed to couple selectively a modified octa-peptide, that is able to gel at low temperature, to the prototypical thermoresponsive polymer poly(N-isopropylacrylamide) to give a bioconjugate that exhibits double thermoresponsiveness. {\textcopyright} The Royal Society of Chemistry.",

keywords = "chemistry: Acrylamides, Calorimetry, Differential Scanning, chemistry: Peptides, chemistry: Polymers, Temperature",

author = "Florentina Stoica and Cameron Alexander and Nicola Tirelli and Miller, {Aline F.} and Alberto Saiani and Aline Saiani",

year = "2008",

doi = "10.1039/b806782a",

language = "English",

pages = "4433--4435",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "37",

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TY - JOUR

T1 - Selective synthesis of double temperature-sensitive polymer-peptide conjugates

AU - Stoica, Florentina

AU - Alexander, Cameron

AU - Tirelli, Nicola

AU - Miller, Aline F.

AU - Saiani, Alberto

AU - Saiani, Aline

PY - 2008

Y1 - 2008

N2 - A novel synthetic route has been developed to couple selectively a modified octa-peptide, that is able to gel at low temperature, to the prototypical thermoresponsive polymer poly(N-isopropylacrylamide) to give a bioconjugate that exhibits double thermoresponsiveness. © The Royal Society of Chemistry.

AB - A novel synthetic route has been developed to couple selectively a modified octa-peptide, that is able to gel at low temperature, to the prototypical thermoresponsive polymer poly(N-isopropylacrylamide) to give a bioconjugate that exhibits double thermoresponsiveness. © The Royal Society of Chemistry.

KW - chemistry: Acrylamides

KW - Calorimetry, Differential Scanning

KW - chemistry: Peptides

KW - chemistry: Polymers

KW - Temperature

U2 - 10.1039/b806782a

DO - 10.1039/b806782a

M3 - Article

SN - 1359-7345

SP - 4433

EP - 4435

JO - Chemical Communications

JF - Chemical Communications

IS - 37

ER -

Selective synthesis of double temperature-sensitive polymer-peptide conjugates

Abstract

Keywords

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