Homonuclear decoupling can give impressive improvements in spectral resolution when overlapping multiplet structures limit the interpretability of NMR spectra. General homodecoupling methods (“pure shift NMR”) typically use either interferogram-style acquisition, which is slow but gives optimum resolution, or real-time acquisition, which is fast but gives broader lines. Here we describe an alternative data acquisition strategy that allows rapid acquisition without resolution loss, illustrating the method with band-selective homodecoupling experiments and demonstrating its advantages over competing methods.
- pure shift NMR
- band-selective decoupling