SERS of meso-droplets supported on superhydrophobic wires allows exquisitely sensitive detection of dipicolinic acid, an Anthrax biomarker, considerably below the infective dose

Melody  Cheung; Wendy W.Y.  Lee; David Cowcher; Royston Goodacre; Steven E. J. Bell

doi:10.1039/C6CC03521C

SERS of meso-droplets supported on superhydrophobic wires allows exquisitely sensitive detection of dipicolinic acid, an Anthrax biomarker, considerably below the infective dose

Melody Cheung, Wendy W.Y. Lee, David Cowcher, Royston Goodacre, Steven E. J. Bell

Queen's University Belfast

Research output: Contribution to journal › Article › peer-review

Abstract

Surface-enhanced Raman measurements of <1 μL analyte/colloid meso-droplets on superhydrophobic wires with hydrophilic tips allowed dipicolinic acid, a spore biomarker for Bacillus anthracis (anthrax), to be detected at 10−6 mol dm−3. This is equivalent to 18 spores, significantly below the infective dose of 104 spores and 2 orders of magnitude better than previous measurements.

Original language	English
Pages (from-to)	9925-9928
Number of pages	4
Journal	Chemical Communications
Volume	52
Early online date	13 Jul 2016
DOIs	https://doi.org/10.1039/C6CC03521C
Publication status	Published - 2016

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Manchester Institute of Biotechnology

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title = "SERS of meso-droplets supported on superhydrophobic wires allows exquisitely sensitive detection of dipicolinic acid, an Anthrax biomarker, considerably below the infective dose",

abstract = "Surface-enhanced Raman measurements of <1 μL analyte/colloid meso-droplets on superhydrophobic wires with hydrophilic tips allowed dipicolinic acid, a spore biomarker for Bacillus anthracis (anthrax), to be detected at 10−6 mol dm−3. This is equivalent to 18 spores, significantly below the infective dose of 104 spores and 2 orders of magnitude better than previous measurements.",

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AU - Cheung, Melody

AU - Lee, Wendy W.Y.

AU - Cowcher, David

AU - Goodacre, Royston

AU - Bell, Steven E. J.

PY - 2016

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AB - Surface-enhanced Raman measurements of <1 μL analyte/colloid meso-droplets on superhydrophobic wires with hydrophilic tips allowed dipicolinic acid, a spore biomarker for Bacillus anthracis (anthrax), to be detected at 10−6 mol dm−3. This is equivalent to 18 spores, significantly below the infective dose of 104 spores and 2 orders of magnitude better than previous measurements.

U2 - 10.1039/C6CC03521C

DO - 10.1039/C6CC03521C

M3 - Article

SN - 1359-7345

VL - 52

SP - 9925

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JO - Chemical Communications

JF - Chemical Communications

ER -

SERS of meso-droplets supported on superhydrophobic wires allows exquisitely sensitive detection of dipicolinic acid, an Anthrax biomarker, considerably below the infective dose

Abstract

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