Serum esterase activities and hyperlipidaemia in the streptozotocin -diabetic rat

Bhartiben N. Patel, Michael I. Mackness, Derek W. Harty, Sharon Arrol, Raymond P. Boot-Hanford, Paul N. Durrington

    Research output: Contribution to journalArticlepeer-review


    The levels of activity of four serum esterases were measured in control and streptozotocin-diabetic rats for a period of 6 months. Pseudocholinesterase activity was significantly elevated in the diabetic rats at all points tested, reaching 250% of control activity at 6 months. Levels of paraoxonase activity progressively decreased with time in the diabetic rats, being 36% lower than in controls at 6 months. No significant differences in either serum arylesterase or carboxylesterase activity between control and diabetic rats were observed. © 1990.
    Original languageEnglish
    Pages (from-to)113-116
    Number of pages3
    JournalBiochimica et Biophysica Acta - General Subjects
    Issue number1
    Publication statusPublished - 20 Jul 1990


    • (Rat)
    • Diabetes
    • Hyperlipidaemia
    • Serum esterase


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