Sildenafil citrate therapy for severe early-onset intrauterine growth restriction

P. Von Dadelszen; S. Dwinnell; L. A. Magee; B. C. Carleton; A. Gruslin; B. Lee; K. I. Lim; R. M. Liston; S. P. Miller; D. Rurak; R. L. Sherlock; M. A. Skoll; M. M. Wareing; P. N. Baker

doi:10.1111/j.1471-0528.2010.02879.x

Sildenafil citrate therapy for severe early-onset intrauterine growth restriction

P. Von Dadelszen, S. Dwinnell, L. A. Magee, B. C. Carleton, A. Gruslin, B. Lee, K. I. Lim, R. M. Liston, S. P. Miller, D. Rurak, R. L. Sherlock, M. A. Skoll, M. M. Wareing, P. N. Baker

Research output: Contribution to journal › Article › peer-review

Abstract

Currently, there is no effective therapy for severe early-onset intrauterine growth restriction (IUGR). Sildenafil citrate vasodilates the myometrial arteries isolated from women with IUGR-complicated pregnancies. Women were offered Sildenafil (25 mg three times daily until delivery) if their pregnancy was complicated by early-onset IUGR [abdominal circumference (AC) <5th percentile] and either the gestational age was

Original language	English
Pages (from-to)	624-628
Number of pages	4
Journal	BJOG: An International Journal of Obstetrics and Gynaecology
Volume	118
Issue number	5
DOIs	https://doi.org/10.1111/j.1471-0528.2010.02879.x
Publication status	Published - Apr 2011

Keywords

Case-control study
In utero therapy
Intrauterine growth restriction
Maternal outcomes
Perinatal outcomes

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10.1111/j.1471-0528.2010.02879.x

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Von Dadelszen, P., Dwinnell, S., Magee, L. A., Carleton, B. C., Gruslin, A., Lee, B., Lim, K. I., Liston, R. M., Miller, S. P., Rurak, D., Sherlock, R. L., Skoll, M. A., Wareing, M. M., & Baker, P. N. (2011). Sildenafil citrate therapy for severe early-onset intrauterine growth restriction. BJOG: An International Journal of Obstetrics and Gynaecology, 118(5), 624-628. https://doi.org/10.1111/j.1471-0528.2010.02879.x

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abstract = "Currently, there is no effective therapy for severe early-onset intrauterine growth restriction (IUGR). Sildenafil citrate vasodilates the myometrial arteries isolated from women with IUGR-complicated pregnancies. Women were offered Sildenafil (25 mg three times daily until delivery) if their pregnancy was complicated by early-onset IUGR [abdominal circumference (AC) <5th percentile] and either the gestational age was",

keywords = "Case-control study, In utero therapy, Intrauterine growth restriction, Maternal outcomes, Perinatal outcomes",

author = "{Von Dadelszen}, P. and S. Dwinnell and Magee, {L. A.} and Carleton, {B. C.} and A. Gruslin and B. Lee and Lim, {K. I.} and Liston, {R. M.} and Miller, {S. P.} and D. Rurak and Sherlock, {R. L.} and Skoll, {M. A.} and Wareing, {M. M.} and Baker, {P. N.}",

year = "2011",

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doi = "10.1111/j.1471-0528.2010.02879.x",

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Von Dadelszen, P, Dwinnell, S, Magee, LA, Carleton, BC, Gruslin, A, Lee, B, Lim, KI, Liston, RM, Miller, SP, Rurak, D, Sherlock, RL, Skoll, MA, Wareing, MM & Baker, PN 2011, 'Sildenafil citrate therapy for severe early-onset intrauterine growth restriction', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 118, no. 5, pp. 624-628. https://doi.org/10.1111/j.1471-0528.2010.02879.x

TY - JOUR

T1 - Sildenafil citrate therapy for severe early-onset intrauterine growth restriction

AU - Von Dadelszen, P.

AU - Dwinnell, S.

AU - Magee, L. A.

AU - Carleton, B. C.

AU - Gruslin, A.

AU - Lee, B.

AU - Lim, K. I.

AU - Liston, R. M.

AU - Miller, S. P.

AU - Rurak, D.

AU - Sherlock, R. L.

AU - Skoll, M. A.

AU - Wareing, M. M.

AU - Baker, P. N.

PY - 2011/4

Y1 - 2011/4

N2 - Currently, there is no effective therapy for severe early-onset intrauterine growth restriction (IUGR). Sildenafil citrate vasodilates the myometrial arteries isolated from women with IUGR-complicated pregnancies. Women were offered Sildenafil (25 mg three times daily until delivery) if their pregnancy was complicated by early-onset IUGR [abdominal circumference (AC) <5th percentile] and either the gestational age was

AB - Currently, there is no effective therapy for severe early-onset intrauterine growth restriction (IUGR). Sildenafil citrate vasodilates the myometrial arteries isolated from women with IUGR-complicated pregnancies. Women were offered Sildenafil (25 mg three times daily until delivery) if their pregnancy was complicated by early-onset IUGR [abdominal circumference (AC) <5th percentile] and either the gestational age was

KW - Case-control study

KW - In utero therapy

KW - Intrauterine growth restriction

KW - Maternal outcomes

KW - Perinatal outcomes

U2 - 10.1111/j.1471-0528.2010.02879.x

DO - 10.1111/j.1471-0528.2010.02879.x

M3 - Article

VL - 118

SP - 624

EP - 628

JO - BJOG

JF - BJOG

SN - 1470-0328

IS - 5

ER -

Sildenafil citrate therapy for severe early-onset intrauterine growth restriction

Abstract

Keywords

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