Sildenafil citrate therapy for severe early-onset intrauterine growth restriction

P. Von Dadelszen, S. Dwinnell, L. A. Magee, B. C. Carleton, A. Gruslin, B. Lee, K. I. Lim, R. M. Liston, S. P. Miller, D. Rurak, R. L. Sherlock, M. A. Skoll, M. M. Wareing, P. N. Baker

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Currently, there is no effective therapy for severe early-onset intrauterine growth restriction (IUGR). Sildenafil citrate vasodilates the myometrial arteries isolated from women with IUGR-complicated pregnancies. Women were offered Sildenafil (25 mg three times daily until delivery) if their pregnancy was complicated by early-onset IUGR [abdominal circumference (AC) <5th percentile] and either the gestational age was
    Original languageEnglish
    Pages (from-to)624-628
    Number of pages4
    JournalBJOG: An International Journal of Obstetrics and Gynaecology
    Volume118
    Issue number5
    DOIs
    Publication statusPublished - Apr 2011

    Keywords

    • Case-control study
    • In utero therapy
    • Intrauterine growth restriction
    • Maternal outcomes
    • Perinatal outcomes

    Fingerprint

    Dive into the research topics of 'Sildenafil citrate therapy for severe early-onset intrauterine growth restriction'. Together they form a unique fingerprint.

    Cite this