TY - JOUR
T1 - Simulating nailfold capillaroscopy sequences to evaluate algorithms for blood flow estimation
AU - Tresadern, P. A.
AU - Berks, M.
AU - Murray, Andrea
AU - Dinsdale, Graham
AU - Taylor, C. J.
AU - Herrick, A. L.
PY - 2013
Y1 - 2013
N2 - The effects of systemic sclerosis (SSc) - a disease of the connective tissue causing blood flow problems that can require amputation of the fingers - can be observed indirectly by imaging the capillaries at the nailfold, though taking quantitative measures such as blood flow to diagnose the disease and monitor its progression is not easy. Optical flow algorithms may be applied, though without ground truth (i.e. known blood flow) it is hard to evaluate their accuracy. We propose an image model that generates realistic capillaroscopy videos with known flow, and use this model to quantify the effect of flow rate, cell density and contrast (among others) on estimated flow. This resource will help researchers to design systems that are robust under real-world conditions. © 2013 IEEE.
AB - The effects of systemic sclerosis (SSc) - a disease of the connective tissue causing blood flow problems that can require amputation of the fingers - can be observed indirectly by imaging the capillaries at the nailfold, though taking quantitative measures such as blood flow to diagnose the disease and monitor its progression is not easy. Optical flow algorithms may be applied, though without ground truth (i.e. known blood flow) it is hard to evaluate their accuracy. We propose an image model that generates realistic capillaroscopy videos with known flow, and use this model to quantify the effect of flow rate, cell density and contrast (among others) on estimated flow. This resource will help researchers to design systems that are robust under real-world conditions. © 2013 IEEE.
UR - https://www.scopus.com/pages/publications/84886516411
U2 - 10.1109/EMBC.2013.6610081
DO - 10.1109/EMBC.2013.6610081
M3 - Article
C2 - 24110268
SN - 0589-1019
SP - 2636
EP - 2639
JO - Annual International Conference of the IEEE Engineering in Medicine and Biology. Proceedings
JF - Annual International Conference of the IEEE Engineering in Medicine and Biology. Proceedings
M1 - 6610081
ER -