Simultaneous registration, segmentation and modelling of structure in groups of medical images

V. Petrović, T. Cootes, C. Twining, C. Taylor, Vladimir Petrovic

    Research output: Chapter in Book/Conference proceedingConference contribution

    Abstract

    We address the problem of extracting information from groups of medical images of the same anatomy. We describe an algorithm which simultaneously segments and registers a set of such images, incrementally constructing a model of their structure and the correspondences across the set. The framework explicitly models the fraction of each tissue type, rather than the expected intensity in each voxel, to decouple the model from details of the imaging sequence and modality. When estimating the optimal deformation field, the current image is compared to a reconstructed image, generated from the model tissue fractions and the current estimate of intensity distributions for each tissue type in the current image (i.e. an estimate of how the model would appear given the imaging conditions for that image). We describe the algorithm in detail and present results of applying it to a set of MR images of the brain. © 2007 IEEE.
    Original languageEnglish
    Title of host publication2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings|IEEE Int. Symp. Biomed. Imag. Nano Macro Proc.
    PublisherIEEE
    Pages1-4
    Number of pages3
    ISBN (Print)1424406722, 9781424406722
    DOIs
    Publication statusPublished - 2007
    Event2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07 - Arlington, VA
    Duration: 1 Jul 2007 → …

    Conference

    Conference2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07
    CityArlington, VA
    Period1/07/07 → …

    Keywords

    • Image registration
    • Segmentation
    • Structure modelling of medical images

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