Abstract
We report on studies of reactions of singlet oxygen with carotenoids and retinoids and a range of free radical studies on carotenoids and retinoids with emphasis on recent work, dietary carotenoids and the role of oxygen in biological processes. Many previous reviews are cited and updated together with new data not previously reviewed. The review does not deal with computational studies but the emphasis is on laboratory-based results. We contrast the ease of study of both singlet oxygen and polyene radical cations compared to neutral radicals. Of particular interest is the switch from anti- to pro-oxidant behavior of a carotenoid with change of oxygen concentration: results for lycopene in a cellular model system show total protection of the human cells studied at zero oxygen concentration, but zero protection at 100% oxygen concentration.
| Original language | English |
|---|---|
| Journal | Antioxidants |
| Volume | 7 |
| Issue number | 1 |
| Early online date | 1 Jan 2018 |
| DOIs | |
| Publication status | Published - 2018 |
Research Beacons, Institutes and Platforms
- Dalton Nuclear Institute