SIRF: Synergistic Image Reconstruction Framework

Evgueni Ovtchinnikov, Richard Brown, Christoph Kolbitsch, Edoardo Pasca, Casper da Costa-Luis, Ashley G. Gillman, Benjamin A. Thomas, Nikos Efthimiou, Johannes Mayer, Palak Wadhwa, Matthias J. Ehrhardt, Sam Ellis, Jakob Jorgensen, Julian Matthews, Claudia Prieto, Andrew J. Reader, Charalampos Tsoumpas, Martin Turner, David Atkinson, Kris Thielemans

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The combination of positron emission tomography (PET) with magnetic resonance (MR) imaging opens the way to more accurate diagnosis and improved patient management. At present, the data acquired by PET-MR scannersare essentially processed separately, but the opportunity to improve accuracy of the tomographic reconstruction via synergy of the two imaging techniques is an active area of research. In this paper, we present Release 2.1.0 of the CCP-PETMR Synergistic Image Reconstruction Framework (SIRF) software suite, providing an opensource software platform for ecient implementation and validation of novel reconstruction algorithms. SIRF provides user-friendly Python and MATLAB binterfaces built on top of C++ libraries. SIRF uses advanced PET and MR reconstruction software packages and tools. Currently, for PET this is Software for Tomographic Image Reconstruction (STIR); for MR, Gadgetron and ISMRMRD; and for image registration tools, NiftyReg. The software aims to be capable of reconstructing images from acquired scanner data, whilst being simple enough to be used for educational purposes.
Original languageEnglish
JournalComputer Physics Communications
Early online date5 Dec 2019
Publication statusPublished - 2020


  • Image Reconstruction
  • PET-MR
  • Multi-modality
  • Medical Imaging
  • Open-Source Software


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  • SIRF: Synergistic Image Reconstruction Framework

    Ovtchinnikov, E. (Contributor), Brown, R. (Contributor), Kolbitsch, C. (Contributor), Pasca, E. (Contributor), da Costa-Luis, C. (Contributor), Gillman, A. G. (Contributor), Thomas, B. A. (Contributor), Efthimiou, N. (Contributor), Mayer, J. (Contributor), Wadhwa, P. (Contributor), Ehrhardt, M. J. (Contributor), Ellis, S. (Contributor), Jørgensen, J. S. (Contributor), Matthews, J. (Contributor), Prieto, C. (Contributor), Reader, A. J. (Contributor), Tsoumpas, C. (Contributor), Turner, M. (Contributor), Atkinson, D. (Contributor) & Thielemans, K. (Contributor), Mendeley Data, 9 Jan 2020


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