SIRT1 activity orchestrates ECM expression during hESC-chondrogenic differentiation

Biochemistry, Genetics and Molecular Biology

• Sirtuin1 100%
• Embryonic Stem Cell 100%
• Glycosaminoglycan 50%
• Chondrocyte 30%
• Aggrecan 30%
• SOX5 20%
• Epigenetic Modification 10%
• Chromatin Immunoprecipitation 10%
• Matrix Protein 10%
• Type II Collagen 10%
• Enhancer Region 10%
• Gene Expression 10%
• Homeostasis 10%
• Mediator 10%
• Protein Biosynthesis 10%
• Transcription Factors 10%
• Cell Function 10%
• Downregulation 10%

Pharmacology, Toxicology and Pharmaceutical Science

• N Acetylgalactosaminyltransferase 20%
• N [2 [3 (1 piperazinylmethyl)imidazo[2,1 B]thiazol 6 Yl]phenyl] 2 Quinoxalinecarboxamide 20%

Medicine and Dentistry

• N Acetylgalactosaminyltransferase 10%
• Selisistat 10%
• SRT1720 10%