SIVagm Infection in Wild African Green Monkeys from South Africa: Epidemiology, Natural History, and Evolutionary Considerations

Dongzhu Ma, Anna Jasinska, Jan Kristoff, J. Paul Grobler, Trudy Turner, Yoon Jung, Christopher Schmitt, Kevin Raehtz, Felix Feyertag, Natalie Martinez Sosa, Viskam Wijewardana, Donald S. Burke, David L. Robertson, Russell Tracy, Ivona Pandrea, Nelson Freimer, Cristian Apetrei

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Pathogenesis studies of SIV infection have not been performed to date in wild monkeys due to difficulty in collecting and storing samples on site and the lack of analytical reagents covering the extensive SIV diversity. We performed a large scale study of molecular epidemiology and natural history of SIVagm infection in 225 free-ranging AGMs from multiple locations in South Africa. SIV prevalence (established by sequencing pol, env, and gag) varied dramatically between infant/juvenile (7%) and adult animals (68%) (p
    Original languageEnglish
    Article numbere1003011
    JournalPL o S Pathogens
    Volume9
    Issue number1
    DOIs
    Publication statusPublished - Jan 2013

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