Skin as an endocrine organ: implications for its function

Andrzej Slominski, Jacobo Wortsman, Ralf Paus, Peter M. Elias, Desmond J. Tobin, Kenneth R. Feingold

    Research output: Contribution to journalArticlepeer-review


    Described as the body's largest organ, the skin is strategically located at the interface with the external environment where it has evolved to detect, integrate and respond to a diverse range of stressors. A flurry of recent findings has established the skin as an important peripheral (neuro)endocrine organ that is tightly networked to central stress axes. This capability is contributing to the maintenance of body homeostasis, and in this way could be harnessed for therapeutic strategies. © 2008 Elsevier Ltd. All rights reserved.
    Original languageEnglish
    Pages (from-to)e137-e144
    JournalDrug Discovery Today: Disease Mechanisms
    Issue number2
    Publication statusPublished - Jun 2008


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