Skin as an endocrine organ: implications for its function

Andrzej Slominski; Jacobo Wortsman; Ralf Paus; Peter M. Elias; Desmond J. Tobin; Kenneth R. Feingold

doi:10.1016/j.ddmec.2008.04.004

Skin as an endocrine organ: implications for its function

Andrzej Slominski, Jacobo Wortsman, Ralf Paus, Peter M. Elias, Desmond J. Tobin, Kenneth R. Feingold

Research output: Contribution to journal › Article › peer-review

Abstract

Described as the body's largest organ, the skin is strategically located at the interface with the external environment where it has evolved to detect, integrate and respond to a diverse range of stressors. A flurry of recent findings has established the skin as an important peripheral (neuro)endocrine organ that is tightly networked to central stress axes. This capability is contributing to the maintenance of body homeostasis, and in this way could be harnessed for therapeutic strategies. © 2008 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	e137-e144
Journal	Drug Discovery Today: Disease Mechanisms
Volume	5
Issue number	2
DOIs	https://doi.org/10.1016/j.ddmec.2008.04.004
Publication status	Published - Jun 2008

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10.1016/j.ddmec.2008.04.004

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abstract = "Described as the body's largest organ, the skin is strategically located at the interface with the external environment where it has evolved to detect, integrate and respond to a diverse range of stressors. A flurry of recent findings has established the skin as an important peripheral (neuro)endocrine organ that is tightly networked to central stress axes. This capability is contributing to the maintenance of body homeostasis, and in this way could be harnessed for therapeutic strategies. {\textcopyright} 2008 Elsevier Ltd. All rights reserved.",

author = "Andrzej Slominski and Jacobo Wortsman and Ralf Paus and Elias, {Peter M.} and Tobin, {Desmond J.} and Feingold, {Kenneth R.}",

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AU - Wortsman, Jacobo

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AU - Tobin, Desmond J.

AU - Feingold, Kenneth R.

PY - 2008/6

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AB - Described as the body's largest organ, the skin is strategically located at the interface with the external environment where it has evolved to detect, integrate and respond to a diverse range of stressors. A flurry of recent findings has established the skin as an important peripheral (neuro)endocrine organ that is tightly networked to central stress axes. This capability is contributing to the maintenance of body homeostasis, and in this way could be harnessed for therapeutic strategies. © 2008 Elsevier Ltd. All rights reserved.

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DO - 10.1016/j.ddmec.2008.04.004

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Skin as an endocrine organ: implications for its function

Abstract

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