Social support decreases depressogenic effect of low-dose interferon alpha treatment in melanoma patients.

Péter Kovács; Gitta Pánczél; Tímea Balatoni; Gabriella Liszkay; Xenia Gonda; Gyorgy Bagdy; Gabriella Juhasz

doi:10.1016/j.jpsychores.2015.03.005

Social support decreases depressogenic effect of low-dose interferon alpha treatment in melanoma patients.

Péter Kovács
, Gitta Pánczél
, Tímea Balatoni
, Gabriella Liszkay
, Xenia Gonda
, Gyorgy Bagdy
, Gabriella Juhasz

Research output: Contribution to journal › Article › peer-review

Abstract

OBJECTIVE: The most frequent serious psychological side effect of immune therapies is depression. In the present study, we tested whether social support, as a positive environmental effect, is able to moderate depression or anxiety symptoms in melanoma patients during adjuvant low-dose interferon treatment. METHODS: Hundred and twenty-seven melanoma patients with negative psychiatric history were included in our longitudinal study and followed up for one year. Depression and anxiety symptoms were measured six times during treatment: at baseline, at 1st, 3rd, 6th, 9th and 12th month of the therapy. In addition, social support was investigated with the Social Dimension Scale. RESULTS: Depressive symptoms significantly increased during the 12-month follow-up period (p

Original language	English
Journal	Journal of psychosomatic research
Volume	78
Issue number	6
DOIs	https://doi.org/10.1016/j.jpsychores.2015.03.005
Publication status	Published - Jun 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Anxiety
Depression
Interferon
Malignant melanoma
Proinflammatory cytokine pathway
Social support

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10.1016/j.jpsychores.2015.03.005

Cite this

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title = "Social support decreases depressogenic effect of low-dose interferon alpha treatment in melanoma patients.",

abstract = "OBJECTIVE: The most frequent serious psychological side effect of immune therapies is depression. In the present study, we tested whether social support, as a positive environmental effect, is able to moderate depression or anxiety symptoms in melanoma patients during adjuvant low-dose interferon treatment. METHODS: Hundred and twenty-seven melanoma patients with negative psychiatric history were included in our longitudinal study and followed up for one year. Depression and anxiety symptoms were measured six times during treatment: at baseline, at 1st, 3rd, 6th, 9th and 12th month of the therapy. In addition, social support was investigated with the Social Dimension Scale. RESULTS: Depressive symptoms significantly increased during the 12-month follow-up period (p",

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AU - Kovács, Péter

AU - Pánczél, Gitta

AU - Balatoni, Tímea

AU - Liszkay, Gabriella

AU - Gonda, Xenia

AU - Bagdy, Gyorgy

AU - Juhasz, Gabriella

PY - 2015/6

Y1 - 2015/6

N2 - OBJECTIVE: The most frequent serious psychological side effect of immune therapies is depression. In the present study, we tested whether social support, as a positive environmental effect, is able to moderate depression or anxiety symptoms in melanoma patients during adjuvant low-dose interferon treatment. METHODS: Hundred and twenty-seven melanoma patients with negative psychiatric history were included in our longitudinal study and followed up for one year. Depression and anxiety symptoms were measured six times during treatment: at baseline, at 1st, 3rd, 6th, 9th and 12th month of the therapy. In addition, social support was investigated with the Social Dimension Scale. RESULTS: Depressive symptoms significantly increased during the 12-month follow-up period (p

AB - OBJECTIVE: The most frequent serious psychological side effect of immune therapies is depression. In the present study, we tested whether social support, as a positive environmental effect, is able to moderate depression or anxiety symptoms in melanoma patients during adjuvant low-dose interferon treatment. METHODS: Hundred and twenty-seven melanoma patients with negative psychiatric history were included in our longitudinal study and followed up for one year. Depression and anxiety symptoms were measured six times during treatment: at baseline, at 1st, 3rd, 6th, 9th and 12th month of the therapy. In addition, social support was investigated with the Social Dimension Scale. RESULTS: Depressive symptoms significantly increased during the 12-month follow-up period (p

KW - Anxiety

KW - Depression

KW - Interferon

KW - Malignant melanoma

KW - Proinflammatory cytokine pathway

KW - Social support

U2 - 10.1016/j.jpsychores.2015.03.005

DO - 10.1016/j.jpsychores.2015.03.005

M3 - Article

C2 - 25801845

SN - 1879-1360

VL - 78

JO - Journal of psychosomatic research

JF - Journal of psychosomatic research

IS - 6

ER -

Social support decreases depressogenic effect of low-dose interferon alpha treatment in melanoma patients.

Abstract

UN SDGs

Keywords

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