Software for genome mapping by fingerprinting techniques

J. Sulston, F. Mallett, R. Staden, R. Durbin, T. Horsnell, A. Coulson

    Research output: Contribution to journalArticlepeer-review


    A genome mapping package has been developed for reading and assembling data from clones analysed by restriction enzyme fragmentation and polyacrylamide gel electrophoresis. The package comprises: data entry; matching; assembly; statistical analysis; modelling. Data entry can be either manual or by a semiautomatic system based on a scanning densitometer. The primary emphasis in the analytical routines is on flexibility and interactive convenience, so that the operator has full knowledge of and control over the growing map, but a variety of automatic options are included. The package continually grows to meet the needs of the Caenorhabditis project.
    Original languageEnglish
    Pages (from-to)125-132
    Number of pages7
    JournalComputer Applications in the Biosciences
    Issue number1
    Publication statusPublished - Mar 1988


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