Solid-phase approach to tetrahydroquinolones using a sulfur linker cleaved by SmI2

Kristy L. Turner, Thomas M. Baker, Saidul Islam, David J. Procter, Mark Stefaniak

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A sulfur α-heteroatom-substituted carbonyl (HASC) linker has been utilized in a solid-phase approach to tetrahydroquinolones. The route illustrates the compatibility of the linker system with palladium-catalyzed transformations and its utility for library synthesis. The linker is cleaved by electron transfer from samarium(II) iodide. © 2006 American Chemical Society.
    Original languageEnglish
    Pages (from-to)329-332
    Number of pages3
    JournalOrganic Letters
    Volume8
    Issue number2
    DOIs
    Publication statusPublished - 19 Jan 2006

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