Solid-phase approach to tetrahydroquinolones using a sulfur linker cleaved by SmI2

Kristy L. Turner; Thomas M. Baker; Saidul Islam; David J. Procter; Mark Stefaniak

doi:10.1021/ol052730n

Solid-phase approach to tetrahydroquinolones using a sulfur linker cleaved by SmI2

Kristy L. Turner, Thomas M. Baker, Saidul Islam, David J. Procter, Mark Stefaniak

Research output: Contribution to journal › Article › peer-review

Abstract

A sulfur α-heteroatom-substituted carbonyl (HASC) linker has been utilized in a solid-phase approach to tetrahydroquinolones. The route illustrates the compatibility of the linker system with palladium-catalyzed transformations and its utility for library synthesis. The linker is cleaved by electron transfer from samarium(II) iodide. © 2006 American Chemical Society.

Original language	English
Pages (from-to)	329-332
Number of pages	3
Journal	Organic Letters
Volume	8
Issue number	2
DOIs	https://doi.org/10.1021/ol052730n
Publication status	Published - 19 Jan 2006

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10.1021/ol052730n

CCDC 285018: Experimental Crystal Structure Determination
Turner, K. L. (Contributor), Baker, T. M. (Contributor), Islam, S. (Contributor), Procter, D. (Contributor) & Stefaniak, M. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2006
DOI: 10.5517/cc9kl4k, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc9kl4k&sid=DataCite
Dataset
CCDC 285210: Experimental Crystal Structure Determination
Turner, K. L. (Contributor), Baker, T. M. (Contributor), Islam, S. (Contributor), Procter, D. (Contributor) & Stefaniak, M. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2006
DOI: 10.5517/cc9ksby, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc9ksby&sid=DataCite
Dataset
CCDC 283479: Experimental Crystal Structure Determination
Turner, K. L. (Contributor), Baker, T. M. (Contributor), Islam, S. (Contributor), Procter, D. (Contributor) & Stefaniak, M. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2006
DOI: 10.5517/cc9hzh7, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc9hzh7&sid=DataCite
Dataset

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@article{6237639b2024484f976bf407b2da0eb2,

title = "Solid-phase approach to tetrahydroquinolones using a sulfur linker cleaved by SmI2",

abstract = "A sulfur α-heteroatom-substituted carbonyl (HASC) linker has been utilized in a solid-phase approach to tetrahydroquinolones. The route illustrates the compatibility of the linker system with palladium-catalyzed transformations and its utility for library synthesis. The linker is cleaved by electron transfer from samarium(II) iodide. {\textcopyright} 2006 American Chemical Society.",

author = "Turner, \{Kristy L.\} and Baker, \{Thomas M.\} and Saidul Islam and Procter, \{David J.\} and Mark Stefaniak",

year = "2006",

month = jan,

day = "19",

doi = "10.1021/ol052730n",

language = "English",

volume = "8",

pages = "329--332",

journal = "Organic Letters",

issn = "1523-7052",

publisher = "American Chemical Society",

number = "2",

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TY - JOUR

T1 - Solid-phase approach to tetrahydroquinolones using a sulfur linker cleaved by SmI2

AU - Turner, Kristy L.

AU - Baker, Thomas M.

AU - Islam, Saidul

AU - Procter, David J.

AU - Stefaniak, Mark

PY - 2006/1/19

Y1 - 2006/1/19

N2 - A sulfur α-heteroatom-substituted carbonyl (HASC) linker has been utilized in a solid-phase approach to tetrahydroquinolones. The route illustrates the compatibility of the linker system with palladium-catalyzed transformations and its utility for library synthesis. The linker is cleaved by electron transfer from samarium(II) iodide. © 2006 American Chemical Society.

AB - A sulfur α-heteroatom-substituted carbonyl (HASC) linker has been utilized in a solid-phase approach to tetrahydroquinolones. The route illustrates the compatibility of the linker system with palladium-catalyzed transformations and its utility for library synthesis. The linker is cleaved by electron transfer from samarium(II) iodide. © 2006 American Chemical Society.

U2 - 10.1021/ol052730n

DO - 10.1021/ol052730n

M3 - Article

SN - 1523-7052

VL - 8

SP - 329

EP - 332

JO - Organic Letters

JF - Organic Letters

IS - 2

ER -

Solid-phase approach to tetrahydroquinolones using a sulfur linker cleaved by SmI2

Abstract

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Datasets

CCDC 285018: Experimental Crystal Structure Determination

CCDC 285210: Experimental Crystal Structure Determination

CCDC 283479: Experimental Crystal Structure Determination

Cite this