Somatic glypican 3 (GPC3) mutations in Wilms' tumour

G. R M White, A. M. Kelsey, J. M. Varley, Jillian M. Birch

Research output: Contribution to journalArticlepeer-review


Tumour and normal tissue from 41 mate cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumour development. © 2002 Cancer Research UK.
Original languageEnglish
Pages (from-to)1920-1922
Number of pages2
JournalBritish Journal of Cancer
Issue number12
Publication statusPublished - 17 Jun 2002


  • Glypican 3
  • Mutation
  • Wilms' tumour


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