Somatic glypican 3 (GPC3) mutations in Wilms' tumour

G. R M White; A. M. Kelsey; J. M. Varley; Jillian M. Birch

doi:10.1038/sj.bjc.6600417

Somatic glypican 3 (GPC3) mutations in Wilms' tumour

G. R M White, A. M. Kelsey, J. M. Varley, Jillian M. Birch

Cancer Research UK Manchester Institute

Research output: Contribution to journal › Article › peer-review

Abstract

Tumour and normal tissue from 41 mate cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumour development. © 2002 Cancer Research UK.

Original language	English
Pages (from-to)	1920-1922
Number of pages	2
Journal	British Journal of Cancer
Volume	86
Issue number	12
DOIs	https://doi.org/10.1038/sj.bjc.6600417
Publication status	Published - 17 Jun 2002

Keywords

Glypican 3
Mutation
Wilms' tumour

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/sj.bjc.6600417

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title = "Somatic glypican 3 (GPC3) mutations in Wilms' tumour",

abstract = "Tumour and normal tissue from 41 mate cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumour development. {\textcopyright} 2002 Cancer Research UK.",

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AU - White, G. R M

AU - Kelsey, A. M.

AU - Varley, J. M.

AU - Birch, Jillian M.

PY - 2002/6/17

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AB - Tumour and normal tissue from 41 mate cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumour development. © 2002 Cancer Research UK.

KW - Glypican 3

KW - Mutation

KW - Wilms' tumour

U2 - 10.1038/sj.bjc.6600417

DO - 10.1038/sj.bjc.6600417

M3 - Article

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JO - BJC

JF - BJC

SN - 0007-0920

IS - 12

ER -

Somatic glypican 3 (GPC3) mutations in Wilms' tumour

Abstract

Keywords

UN SDGs

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