Abstract
We report the spontaneous regression of an Epstein-Barr virus-associated monoclonal lymphoid proliferation in an immunocompetent child. A 2-year-old male with acute otitis media presented with a right-sided facial palsy secondary to acute mastoiditis. During mastoid decompression a polypoid mass, a histologically diffuse large B cell lymphoma, was found. Staging revealed localized disease. At surgical re-exploration 5 weeks later the disease had resolved. Retrospective serological testing was consistent with an acute Epstein-Barr viral infection and in situ hybridization of the tumour tissue was positive for Epstein-Barr RNA. © 2008 Wiley-Liss, Inc.
Original language | English |
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Pages (from-to) | 557-559 |
Number of pages | 2 |
Journal | Pediatric Blood and Cancer |
Volume | 51 |
Issue number | 4 |
DOIs | |
Publication status | Published - Oct 2008 |
Keywords
- DLBCL
- EBV
- Lymphoma
- Spontaneous regression
- Spontaneous resolution