Stem cells and debrided waste: two alternative sources of cells for transplantation of cartilage

L. C. Biant, G. Bentley

Research output: Contribution to journalArticlepeer-review

Abstract

Implantation of autologous chondrocytes and matrix autologous chondrocytes are techniques of cartilage repair used in the young adult knee which require harvesting of healthy cartilage and which may cause iatrogenic damage to the joint. This study explores alternative sources of autologous cells. Chondrocytes obtained from autologous bone-marrow-derived cells and those from the damaged cartilage within the lesion itself are shown to be viable alternatives to harvest-derived cells. A sufficient number and quality of cells were obtained by the new techniques and may be suitable for autologous chondrocyte and matrix autologous chondrocyte implantation.

Original languageEnglish
Pages (from-to)1110-4
Number of pages5
JournalThe Journal of bone and joint surgery. British volume
Volume89
Issue number8
DOIs
Publication statusPublished - Aug 2007

Keywords

  • Adolescent
  • Adult
  • Cartilage, Articular/injuries
  • Cell Transplantation/methods
  • Chondrocytes/transplantation
  • Debridement
  • Female
  • Humans
  • Knee Injuries/prevention & control
  • Knee Joint/pathology
  • Male
  • Stem Cells/cytology
  • Transplantation, Autologous

Fingerprint

Dive into the research topics of 'Stem cells and debrided waste: two alternative sources of cells for transplantation of cartilage'. Together they form a unique fingerprint.

Cite this