Stereospecific oxidation by Compound I of Cytochrome P450 does not proceed in a concerted synchronous manner

S. P. De Visser; F. Ogliaro; S. Shaik

doi:10.1039/b105571m

Stereospecific oxidation by Compound I of Cytochrome P450 does not proceed in a concerted synchronous manner

Research output: Contribution to journal › Article › peer-review

Abstract

Calculations show that the transition structure for the synchronous oxygen transfer by Compound I is a second order saddle point. The process is unlikely.

Original language	English
Pages (from-to)	2322-2323
Number of pages	1
Journal	Chemical Communications
Issue number	22
DOIs	https://doi.org/10.1039/b105571m
Publication status	Published - 21 Nov 2001

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title = "Stereospecific oxidation by Compound I of Cytochrome P450 does not proceed in a concerted synchronous manner",

abstract = "Calculations show that the transition structure for the synchronous oxygen transfer by Compound I is a second order saddle point. The process is unlikely.",

author = "{De Visser}, {S. P.} and F. Ogliaro and S. Shaik",

year = "2001",

month = nov,

day = "21",

doi = "10.1039/b105571m",

language = "English",

pages = "2322--2323",

journal = "Chemical Communications",

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T1 - Stereospecific oxidation by Compound I of Cytochrome P450 does not proceed in a concerted synchronous manner

AU - De Visser, S. P.

AU - Ogliaro, F.

AU - Shaik, S.

PY - 2001/11/21

Y1 - 2001/11/21

N2 - Calculations show that the transition structure for the synchronous oxygen transfer by Compound I is a second order saddle point. The process is unlikely.

AB - Calculations show that the transition structure for the synchronous oxygen transfer by Compound I is a second order saddle point. The process is unlikely.

U2 - 10.1039/b105571m

DO - 10.1039/b105571m

M3 - Article

SN - 1359-7345

SP - 2322

EP - 2323

JO - Chemical Communications

JF - Chemical Communications

IS - 22

ER -

Stereospecific oxidation by Compound I of Cytochrome P450 does not proceed in a concerted synchronous manner

Abstract

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