Strategies for regeneration of the intervertebral disc

    Research output: Contribution to journalArticlepeer-review


    Low back pain resulting from degenerative disc disease is the most common cause of disability in the UK. Current low back pain treatments are aimed at either treating the symptoms of pain, or removing the source of pain itself, but do not address the biological basis of the disease. Our increasing understanding of the molecular biological basis for degenerative disc disease has enabled the development of strategies aimed at tackling the causes of degeneration. Here we review the progress that has been made in strategies using cells, biomaterials and growth factors aimed at regenerating the human intervertebral disc. © 2008 Future Medicine Ltd.
    Original languageEnglish
    Pages (from-to)715-729
    Number of pages14
    JournalRegenerative Medicine
    Issue number5
    Publication statusPublished - 2008


    • Intervertebral disc
    • Mesenchymal stem cell
    • Nucleus pulposus
    • Regenerative medicine
    • Tissue engineering


    Dive into the research topics of 'Strategies for regeneration of the intervertebral disc'. Together they form a unique fingerprint.

    Cite this