Streamlined recycling of S-adenosylmethionine

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    S-adenosylmethionine (SAM)-dependent methyltransferase enzymes have significant synthetic potential, but their utility as biocatalysts has been limited by the availability of SAM. An elegant and simple method addressing this long-standing problem has now been developed using a halide methyltransferase (HMT) enzyme for SAM regeneration in vitro.

    Original languageEnglish
    JournalNature Catalysis
    Publication statusPublished - 8 Jul 2019


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