Successful ABO incompatible renal transplantation following rituximab and DFPP after failed immunoadsorption

Shenal Thalgahagoda; Nicholas J A Webb; Denise Roberts; Allison Birch; David V. Milford; Afshin Tavakoli; Mohan Shenoy

doi:10.1111/petr.12227

Successful ABO incompatible renal transplantation following rituximab and DFPP after failed immunoadsorption

Shenal Thalgahagoda, Nicholas J A Webb, Denise Roberts, Allison Birch, David V. Milford, Afshin Tavakoli, Mohan Shenoy

Research output: Contribution to journal › Article › peer-review

Abstract

Effective antibody removal using PE, DFPP and IA has led to increased access to live donor organs through ABOi RT for patients with chronic kidney disease. However, there have been no head-to-head comparator studies between these modalities, and the choice of technique is usually influenced by cost and institutional preference. We describe the clinical course of a child undergoing ABOi RT, in whom IA without preconditioning with rituximab did not achieve a satisfactory reduction in the antibody titers, who went on to have a successful living donor RT following rituximab and DFPP. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Original language	English
Pages (from-to)	E74-E76
Journal	Pediatric transplantation
Volume	18
Issue number	3
DOIs	https://doi.org/10.1111/petr.12227
Publication status	Published - 2014

Keywords

ABOi kidney transplant
double filtration plasmapheresis
immunoadsorption
rituximab

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/petr.12227

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title = "Successful ABO incompatible renal transplantation following rituximab and DFPP after failed immunoadsorption",

abstract = "Effective antibody removal using PE, DFPP and IA has led to increased access to live donor organs through ABOi RT for patients with chronic kidney disease. However, there have been no head-to-head comparator studies between these modalities, and the choice of technique is usually influenced by cost and institutional preference. We describe the clinical course of a child undergoing ABOi RT, in whom IA without preconditioning with rituximab did not achieve a satisfactory reduction in the antibody titers, who went on to have a successful living donor RT following rituximab and DFPP. {\textcopyright} 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",

keywords = "ABOi kidney transplant, double filtration plasmapheresis, immunoadsorption, rituximab",

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T1 - Successful ABO incompatible renal transplantation following rituximab and DFPP after failed immunoadsorption

AU - Thalgahagoda, Shenal

AU - Webb, Nicholas J A

AU - Roberts, Denise

AU - Birch, Allison

AU - Milford, David V.

AU - Tavakoli, Afshin

AU - Shenoy, Mohan

PY - 2014

Y1 - 2014

N2 - Effective antibody removal using PE, DFPP and IA has led to increased access to live donor organs through ABOi RT for patients with chronic kidney disease. However, there have been no head-to-head comparator studies between these modalities, and the choice of technique is usually influenced by cost and institutional preference. We describe the clinical course of a child undergoing ABOi RT, in whom IA without preconditioning with rituximab did not achieve a satisfactory reduction in the antibody titers, who went on to have a successful living donor RT following rituximab and DFPP. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

AB - Effective antibody removal using PE, DFPP and IA has led to increased access to live donor organs through ABOi RT for patients with chronic kidney disease. However, there have been no head-to-head comparator studies between these modalities, and the choice of technique is usually influenced by cost and institutional preference. We describe the clinical course of a child undergoing ABOi RT, in whom IA without preconditioning with rituximab did not achieve a satisfactory reduction in the antibody titers, who went on to have a successful living donor RT following rituximab and DFPP. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

KW - ABOi kidney transplant

KW - double filtration plasmapheresis

KW - immunoadsorption

KW - rituximab

U2 - 10.1111/petr.12227

DO - 10.1111/petr.12227

M3 - Article

C2 - 24483150

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VL - 18

SP - E74-E76

JO - Pediatric transplantation

JF - Pediatric transplantation

IS - 3

ER -

Successful ABO incompatible renal transplantation following rituximab and DFPP after failed immunoadsorption

Abstract

Keywords

UN SDGs

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