Successful treatment of severe recalcitrant psoriasis with combination infliximab and methotrexate

B. Kirby; A. M. Marsland; A. J. Carmichael; C. E M Griffiths

doi:10.1046/j.1365-2230.2001.00753.x

Successful treatment of severe recalcitrant psoriasis with combination infliximab and methotrexate

B. Kirby, A. M. Marsland, A. J. Carmichael, C. E M Griffiths

Research output: Contribution to journal › Article › peer-review

Abstract

Plaques of psoriasis contain increased levels of cytokines, including tumour necrosis factor-alpha (TNF-α), which are thought to be essential to the maintenance of the psoriatic process. We report the successful treatment of severe, recalcitrant psoriasis when infliximab (a monoclonal antibody to TNF-α) was used in combination with methotrexate.

Original language	English
Pages (from-to)	27-29
Number of pages	2
Journal	Clinical and Experimental Dermatology
Volume	26
Issue number	1
DOIs	https://doi.org/10.1046/j.1365-2230.2001.00753.x
Publication status	Published - 2001

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@article{632a890ed76a4cb786a372ab021d8160,

title = "Successful treatment of severe recalcitrant psoriasis with combination infliximab and methotrexate",

abstract = "Plaques of psoriasis contain increased levels of cytokines, including tumour necrosis factor-alpha (TNF-α), which are thought to be essential to the maintenance of the psoriatic process. We report the successful treatment of severe, recalcitrant psoriasis when infliximab (a monoclonal antibody to TNF-α) was used in combination with methotrexate.",

author = "B. Kirby and Marsland, {A. M.} and Carmichael, {A. J.} and Griffiths, {C. E M}",

year = "2001",

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language = "English",

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AU - Kirby, B.

AU - Marsland, A. M.

AU - Carmichael, A. J.

AU - Griffiths, C. E M

PY - 2001

Y1 - 2001

N2 - Plaques of psoriasis contain increased levels of cytokines, including tumour necrosis factor-alpha (TNF-α), which are thought to be essential to the maintenance of the psoriatic process. We report the successful treatment of severe, recalcitrant psoriasis when infliximab (a monoclonal antibody to TNF-α) was used in combination with methotrexate.

AB - Plaques of psoriasis contain increased levels of cytokines, including tumour necrosis factor-alpha (TNF-α), which are thought to be essential to the maintenance of the psoriatic process. We report the successful treatment of severe, recalcitrant psoriasis when infliximab (a monoclonal antibody to TNF-α) was used in combination with methotrexate.

U2 - 10.1046/j.1365-2230.2001.00753.x

DO - 10.1046/j.1365-2230.2001.00753.x

M3 - Article

SN - 0307-6938

VL - 26

SP - 27

EP - 29

JO - Clinical and Experimental Dermatology

JF - Clinical and Experimental Dermatology

IS - 1

ER -

Successful treatment of severe recalcitrant psoriasis with combination infliximab and methotrexate

Abstract

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