Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation

Jack L. Martin; Ana S H Costa; Anja V. Gruszczyk; Timothy E. Beach; Fay M. Allen; Hiran Prag; Elizabeth C. Hinchy; Krishnaa Mahbubani; M Hamed; L Tronci; E Nikitopoulou; Andrew M. James; Thomas Krieg; Alan J Robinson; Margaret M. Huang; Stuart T. Caldwell; Angela Logan; Laura Pala; Richard C. Hartley; Christian Frezza; Kourosh Saeb-Parsy; Michael P. Murphy

doi:10.1038/s42255-019-0115-y

Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation

Jack L. Martin, Ana S H Costa, Anja V. Gruszczyk, Timothy E. Beach, Fay M. Allen, Hiran Prag, Elizabeth C. Hinchy, Krishnaa Mahbubani, M Hamed, L Tronci, E Nikitopoulou, Andrew M. James, Thomas Krieg, Alan J Robinson, Margaret M. Huang, Stuart T. Caldwell, Angela Logan, Laura Pala, Richard C. Hartley, Christian FrezzaKourosh Saeb-Parsy, Michael P. Murphy^*

^*Corresponding author for this work

Pharmacy

Research output: Contribution to journal › Letter › peer-review

Original language	English
Pages (from-to)	966–974
Number of pages	9
Journal	Nature Metabolism
Volume	1
Issue number	10
DOIs	https://doi.org/10.1038/s42255-019-0115-y
Publication status	Published - 30 Sept 2019

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Martin, J. L., Costa, A. S. H., Gruszczyk, A. V., Beach, T. E., Allen, F. M., Prag, H., Hinchy, E. C., Mahbubani, K., Hamed, M., Tronci, L., Nikitopoulou, E., James, A. M., Krieg, T., Robinson, A. J., Huang, M. M., Caldwell, S. T., Logan, A., Pala, L., Hartley, R. C., ... Murphy, M. P. (2019). Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation. Nature Metabolism, 1(10), 966–974 . https://doi.org/10.1038/s42255-019-0115-y

@article{2243e8cd929e4b319da47b28cefec4a5,

title = "Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation",

author = "Martin, {Jack L.} and Costa, {Ana S H} and Gruszczyk, {Anja V.} and Beach, {Timothy E.} and Allen, {Fay M.} and Hiran Prag and Hinchy, {Elizabeth C.} and Krishnaa Mahbubani and M Hamed and L Tronci and E Nikitopoulou and James, {Andrew M.} and Thomas Krieg and Robinson, {Alan J} and Huang, {Margaret M.} and Caldwell, {Stuart T.} and Angela Logan and Laura Pala and Hartley, {Richard C.} and Christian Frezza and Kourosh Saeb-Parsy and Murphy, {Michael P.}",

year = "2019",

month = sep,

day = "30",

doi = "10.1038/s42255-019-0115-y",

language = "English",

volume = "1",

pages = "966–974 ",

journal = "Nature Metabolism",

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Martin, JL, Costa, ASH, Gruszczyk, AV, Beach, TE, Allen, FM, Prag, H, Hinchy, EC, Mahbubani, K, Hamed, M, Tronci, L, Nikitopoulou, E, James, AM, Krieg, T, Robinson, AJ, Huang, MM, Caldwell, ST, Logan, A, Pala, L, Hartley, RC, Frezza, C, Saeb-Parsy, K & Murphy, MP 2019, 'Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation', Nature Metabolism, vol. 1, no. 10, pp. 966–974 . https://doi.org/10.1038/s42255-019-0115-y

TY - JOUR

T1 - Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation

AU - Martin, Jack L.

AU - Costa, Ana S H

AU - Gruszczyk, Anja V.

AU - Beach, Timothy E.

AU - Allen, Fay M.

AU - Prag, Hiran

AU - Hinchy, Elizabeth C.

AU - Mahbubani, Krishnaa

AU - Hamed, M

AU - Tronci, L

AU - Nikitopoulou, E

AU - James, Andrew M.

AU - Krieg, Thomas

AU - Robinson, Alan J

AU - Huang, Margaret M.

AU - Caldwell, Stuart T.

AU - Logan, Angela

AU - Pala, Laura

AU - Hartley, Richard C.

AU - Frezza, Christian

AU - Saeb-Parsy, Kourosh

AU - Murphy, Michael P.

PY - 2019/9/30

Y1 - 2019/9/30

UR - http://europepmc.org/abstract/med/32395697

U2 - 10.1038/s42255-019-0115-y

DO - 10.1038/s42255-019-0115-y

M3 - Letter

C2 - 32395697

SN - 2522-5812

VL - 1

SP - 966

EP - 974

JO - Nature Metabolism

JF - Nature Metabolism

IS - 10

ER -

Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation

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