Suitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump

M. Hrubiško; A. T. Mc Gown; J. A. Prendiville; J. A. Radford; N. Thatcher; B. W. Fox

doi:10.1007/BF00686261

Suitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump

M. Hrubiško, A. T. Mc Gown, J. A. Prendiville, J. A. Radford, N. Thatcher, B. W. Fox

Research output: Contribution to journal › Article › peer-review

Abstract

The stability of cisplatin (DDP) solutions (1 and 1.6 mg/ml in saline-mannitol) in plastic infusion bags was studied for up to 14 days at 25° C, 37° C and 60° C. Small changes in the solution were observed, but no evidence of any decomposition product was seen. Some precipitation of DDP was seen in the 1.6-mg/ml solution at the lower temperatures. Fluid loss from the bags was significant at the higher temperatures. © 1992 Springer-Verlag.

Original language	English
Pages (from-to)	252-255
Number of pages	3
Journal	Cancer Chemotherapy and Pharmacology
Volume	29
Issue number	3
DOIs	https://doi.org/10.1007/BF00686261
Publication status	Published - May 1992

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10.1007/BF00686261

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title = "Suitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump",

abstract = "The stability of cisplatin (DDP) solutions (1 and 1.6 mg/ml in saline-mannitol) in plastic infusion bags was studied for up to 14 days at 25° C, 37° C and 60° C. Small changes in the solution were observed, but no evidence of any decomposition product was seen. Some precipitation of DDP was seen in the 1.6-mg/ml solution at the lower temperatures. Fluid loss from the bags was significant at the higher temperatures. {\textcopyright} 1992 Springer-Verlag.",

author = "M. Hrubi{\v s}ko and {Mc Gown}, {A. T.} and Prendiville, {J. A.} and Radford, {J. A.} and N. Thatcher and Fox, {B. W.}",

year = "1992",

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AU - Hrubiško, M.

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AU - Prendiville, J. A.

AU - Radford, J. A.

AU - Thatcher, N.

AU - Fox, B. W.

PY - 1992/5

Y1 - 1992/5

N2 - The stability of cisplatin (DDP) solutions (1 and 1.6 mg/ml in saline-mannitol) in plastic infusion bags was studied for up to 14 days at 25° C, 37° C and 60° C. Small changes in the solution were observed, but no evidence of any decomposition product was seen. Some precipitation of DDP was seen in the 1.6-mg/ml solution at the lower temperatures. Fluid loss from the bags was significant at the higher temperatures. © 1992 Springer-Verlag.

AB - The stability of cisplatin (DDP) solutions (1 and 1.6 mg/ml in saline-mannitol) in plastic infusion bags was studied for up to 14 days at 25° C, 37° C and 60° C. Small changes in the solution were observed, but no evidence of any decomposition product was seen. Some precipitation of DDP was seen in the 1.6-mg/ml solution at the lower temperatures. Fluid loss from the bags was significant at the higher temperatures. © 1992 Springer-Verlag.

U2 - 10.1007/BF00686261

DO - 10.1007/BF00686261

M3 - Article

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SN - 0344-5704

VL - 29

SP - 252

EP - 255

JO - Cancer Chemotherapy and Pharmacology

JF - Cancer Chemotherapy and Pharmacology

IS - 3

ER -

Suitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump

Abstract

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