Surgical outcomes of adult patients with abdominopelvic sarcomas

J.Y. Baik, T. Lee, J. Oates, O. Aziz, M. Wilson, P. Shenjere, J. Shanks, P. Oliveira, J. Wylie, M. Leahy, V. Sangar, N. Clarke

Research output: Contribution to journalMeeting Abstractpeer-review

Abstract

Introduction & Objectives: Abdominopelvic sarcomas are rare soft tissue tumours associated with high rates of local recurrence. Complete macroscopic resection of the tumour remains the primary treatment. This study assesses the surgical outcomes of patients with abdominopelvic sarcomas treated at a single tertiary urology referral centre over a 5-year period. Materials & Methods: Electronic patient records of all abdominopelvic sarcoma resections performed between May 2013 and November 2018 were retrospectively reviewed. The following parameters were assessed: Histology, pre-operative haemoglobin (Hb) level, ECOG performance status, grade, tumour size, stage and margin status. The 8th edition Union for International Cancer Control (UICC) stage classification system was utilised for retroperitoneal sarcoma (RPS) patients. Log-rank and Kaplan-Meir methods were utilised to complete univariate analysis for overall survival (OS) and disease-free survival (DFS). Results: In total, 53 patients with abdominopelvic sarcomas underwent surgical resection. Median age at surgery was 65 years (27-83 years). Median follow-up was 23 months (1-72 months). The 3 year OS and DFS were 74% and 41% respectively. Histologic subtypes are summarised in table 1. The 3 year OS of well-differentiated liposarcoma (WDLPS) and other histologic subtypes (OHS) was 91.7% and 67% respectively (p=0.041). The 3 year DFS of WDLPS and OHS was 92.3% and 19.8% respectively (p
Original languageEnglish
Pages (from-to)e563-e564
JournalEuropean Urology Open Science
Volume19
DOIs
Publication statusPublished - Jul 2020

Research Beacons, Institutes and Platforms

  • Manchester Cancer Research Centre

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