Symposium: innovative techniques in human embryo viability assessment. Assessing embryo viability by measurement of amino acid turnover

RG Sturmey, DR Brison, HJ Leese

    Research output: Contribution to journalArticlepeer-review

    Abstract

    This review assesses the ability of non-invasive 'amino acid profiling' to predict early embryo viability. The history of amino acid supplementation of embryo culture media and the role of amino acids in early embryo development are first considered and these are followed by a review of methods to quantify amino acid depletion and production by single embryos. Data on amino acid profiling of embryos from a number of species are then discussed. It is concluded that this technology has excellent potential to improve the selection of single embryos for transfer in clinical IVF.
    Original languageEnglish
    Pages (from-to)486-496
    JournalReproductive BioMedicine Online
    Volume17
    Issue number4
    DOIs
    Publication statusPublished - Oct 2008

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