Synthesis of mono- and dimannoside phosphoramidite derivatives for solid-phase conjugation to oligonucleotides

Saghir Akhtar, Anne Routledge, Ramila Patel, John M. Gardiner

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Mannose and dimannose derivatives have been prepared with an anomerically-linked hydrophobic spacer, and converted to phosphoramidite derivatives suitable for conjugation to oligoribodeoxynucleotides on a DNA/RNA synthesizer. Synthesis of a monomannoside-linked 15-mer oligoribodeoxynucleotide is reported. © 1995.
    Original languageEnglish
    Pages (from-to)7333-7336
    Number of pages3
    JournalTetrahedron Letters
    Volume36
    Issue number40
    DOIs
    Publication statusPublished - 2 Oct 1995

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