Synthesis of the ABH rings of ecteinascidin 597 using a connective Pummerer-type cyclisation

Laura H S Smith; Trung Thanh Nguyen; Helen F. Sneddon; David J. Procter

doi:10.1039/c1cc13992d

Synthesis of the ABH rings of ecteinascidin 597 using a connective Pummerer-type cyclisation

Laura H S Smith, Trung Thanh Nguyen, Helen F. Sneddon, David J. Procter

Research output: Contribution to journal › Article › peer-review

Abstract

A connective Pummerer-type cyclisation involving a cysteine derivative and an N-benzyl glyoxamide 3 has been applied in an asymmetric synthesis of the protected ABH rings 2 of the antitumour and antimicrobial natural product ecteinascidin 597. © 2011 The Royal Society of Chemistry.

Original language	English
Pages (from-to)	10821-10823
Number of pages	2
Journal	Chemical Communications
Volume	47
Issue number	38
DOIs	https://doi.org/10.1039/c1cc13992d
Publication status	Published - 14 Oct 2011

Access to Document

10.1039/c1cc13992d

CCDC 808088: Experimental Crystal Structure Determination
Smith, L. H. S. (Contributor), Nguyen, T. (Contributor), Sneddon, H. F. (Contributor) & Procter, D. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2012
DOI: 10.5517/ccw3wc6, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccw3wc6&sid=DataCite
Dataset

Cite this

@article{e6d1ffb387c74555a4af2a238b360112,

title = "Synthesis of the ABH rings of ecteinascidin 597 using a connective Pummerer-type cyclisation",

abstract = "A connective Pummerer-type cyclisation involving a cysteine derivative and an N-benzyl glyoxamide 3 has been applied in an asymmetric synthesis of the protected ABH rings 2 of the antitumour and antimicrobial natural product ecteinascidin 597. {\textcopyright} 2011 The Royal Society of Chemistry.",

author = "Smith, {Laura H S} and Nguyen, {Trung Thanh} and Sneddon, {Helen F.} and Procter, {David J.}",

year = "2011",

month = oct,

day = "14",

doi = "10.1039/c1cc13992d",

language = "English",

volume = "47",

pages = "10821--10823",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "38",

}

TY - JOUR

T1 - Synthesis of the ABH rings of ecteinascidin 597 using a connective Pummerer-type cyclisation

AU - Smith, Laura H S

AU - Nguyen, Trung Thanh

AU - Sneddon, Helen F.

AU - Procter, David J.

PY - 2011/10/14

Y1 - 2011/10/14

N2 - A connective Pummerer-type cyclisation involving a cysteine derivative and an N-benzyl glyoxamide 3 has been applied in an asymmetric synthesis of the protected ABH rings 2 of the antitumour and antimicrobial natural product ecteinascidin 597. © 2011 The Royal Society of Chemistry.

AB - A connective Pummerer-type cyclisation involving a cysteine derivative and an N-benzyl glyoxamide 3 has been applied in an asymmetric synthesis of the protected ABH rings 2 of the antitumour and antimicrobial natural product ecteinascidin 597. © 2011 The Royal Society of Chemistry.

U2 - 10.1039/c1cc13992d

DO - 10.1039/c1cc13992d

M3 - Article

VL - 47

SP - 10821

EP - 10823

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 38

ER -

Synthesis of the ABH rings of ecteinascidin 597 using a connective Pummerer-type cyclisation

Abstract

Access to Document

Fingerprint

Datasets

CCDC 808088: Experimental Crystal Structure Determination

Cite this