Synthetic biology advances for pharmaceutical production

R Breitling; E Takano

doi:10.1016/j.copbio.2015.02.004

Synthetic biology advances for pharmaceutical production

Research output: Contribution to journal › Article › peer-review

Abstract

Synthetic biology enables a new generation of microbial engineering for the biotechnological production of pharmaceuticals and other high-value chemicals. This review presents an overview of recent advances in the field, describing new computational and experimental tools for the discovery, optimization and production of bioactive molecules, and outlining progress towards the application of these tools to pharmaceutical production systems.

Original language	English
Pages (from-to)	46-51
Number of pages	5
Journal	Current Opinion in Biotechnology
Volume	35C
DOIs	https://doi.org/10.1016/j.copbio.2015.02.004
Publication status	Published - 2 Mar 2015

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10.1016/j.copbio.2015.02.004

Manchester Synthetic Biology Research Centre for Fine and Speciality Chemicals
Scrutton, N. (PI), Azapagic, A. (CoI), Balmer, A. (CoI), Barran, P. (CoI), Breitling, R. (CoI), Delneri, D. (CoI), Dixon, N. (CoI), Faulon, J.-L. (CoI), Flitsch, S. (CoI), Goble, C. (CoI), Goodacre, R. (CoI), Hay, S. (CoI), Kell, D. (CoI), Leys, D. (CoI), Lloyd, J. (CoI), Lockyer, N. (CoI), Martin, P. (CoI), Micklefield, J. (CoI), Munro, A. (CoI), Pedrosa Mendes, P. (CoI), Randles, S. (CoI), Salehi Yazdi, F. (CoI), Shapira, P. (CoI), Takano, E. (CoI), Turner, N. (CoI) & Winterburn, J. (CoI)
14/11/14 → 13/05/20
Project: Research
13TSB_TIBio: Synthetic Biology for antibiotic discovery and development
Takano, E. (PI)
1/05/14 → 30/04/16
Project: Research

Cite this

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title = "Synthetic biology advances for pharmaceutical production",

abstract = "Synthetic biology enables a new generation of microbial engineering for the biotechnological production of pharmaceuticals and other high-value chemicals. This review presents an overview of recent advances in the field, describing new computational and experimental tools for the discovery, optimization and production of bioactive molecules, and outlining progress towards the application of these tools to pharmaceutical production systems.",

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Synthetic biology advances for pharmaceutical production

Abstract

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Projects

Manchester Synthetic Biology Research Centre for Fine and Speciality Chemicals

13TSB_TIBio: Synthetic Biology for antibiotic discovery and development

Cite this