Tandem indole C-H alkenylation/arylation for tetra-substituted alkene synthesis

Laura Lopez Suarez, Michael F. Greaney

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Alkynyl indoles undergo a novel sequence of Pd-catalysed indole C-H activation/alkyne carbopalladation/arylation, with diaryliodonium salts providing the aryl components. An array of functionalised indole alkenes have been prepared in good to excellent yield, with the reaction being selective for the Z-alkene. © 2011 The Royal Society of Chemistry.
    Original languageEnglish
    Pages (from-to)7992-7994
    Number of pages2
    JournalChemical Communications
    Volume47
    Issue number28
    DOIs
    Publication statusPublished - 28 Jul 2011

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