Abstract
Sanofi-aventis (formerly Aventis) and Regeneron are developing systemic VEGF Trap, a soluble decoy receptor comprising portions of VEGF receptors 1 and 2, for the potential intravenous/subcutaneous treatment of cancer. © The Thomson Corporation.
Original language | English |
---|---|
Pages (from-to) | 493-501 |
Number of pages | 8 |
Journal | Current Opinion in Molecular Therapeutics |
Volume | 7 |
Issue number | 5 |
Publication status | Published - Oct 2005 |
Keywords
- therapeutic use: Angiogenesis Inhibitors
- Animals
- Clinical Trials, Phase I
- Drug Evaluation, Preclinical
- Humans
- Mice
- blood supply: Neoplasms
- antagonists & inhibitors: Vascular Endothelial Growth Factor A
- metabolism: Vascular Endothelial Growth Factor Receptor-1
- metabolism: Vascular Endothelial Growth Factor Receptor-2