Technology evaluation: VEGF Trap (cancer), Regeneron/sanofi-aventis

Sin C. Lau, Daniela D. Rosa, Gordon Jayson

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Sanofi-aventis (formerly Aventis) and Regeneron are developing systemic VEGF Trap, a soluble decoy receptor comprising portions of VEGF receptors 1 and 2, for the potential intravenous/subcutaneous treatment of cancer. © The Thomson Corporation.
    Original languageEnglish
    Pages (from-to)493-501
    Number of pages8
    JournalCurrent Opinion in Molecular Therapeutics
    Volume7
    Issue number5
    Publication statusPublished - Oct 2005

    Keywords

    • therapeutic use: Angiogenesis Inhibitors
    • Animals
    • Clinical Trials, Phase I
    • Drug Evaluation, Preclinical
    • Humans
    • Mice
    • blood supply: Neoplasms
    • antagonists & inhibitors: Vascular Endothelial Growth Factor A
    • metabolism: Vascular Endothelial Growth Factor Receptor-1
    • metabolism: Vascular Endothelial Growth Factor Receptor-2

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