Temporal diffeomorphic free-form deformation for strain quantification in 3D-US images

Mathieu De Craene, Gemma Piella, Nicolas Duchateau, Etel Silva, Adelina Doltra, Hang Gao, Jan D'Hooge, Oscar Camara, Josep Brugada, Marta Sitges, Alejandro F. Frangi

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

This paper presents a new diffeomorphic temporal registration algorithm and its application to motion and strain quantification from a temporal sequence of 3D images. The displacement field is computed by forward eulerian integration of a non-stationary velocity field. The originality of our approach resides in enforcing time consistency by representing the velocity field as a sum of continuous spatiotemporal BSpline kernels. The accuracy of the developed diffeomorphic technique was first compared to a simple pairwise strategy on synthetic US images with known ground truth motion and with several noise levels, being the proposed algorithm more robust to noise than the pairwise case. Our algorithm was then applied to a database of cardiac 3D+t Ultrasound (US) images of the left ventricle acquired from eight healthy volunteers and three Cardiac Resynchronization Therapy (CRT) patients. On healthy cases, the measured regional strain curves provided uniform strain patterns over all myocardial segments in accordance with clinical literature. On CRT patients, the obtained normalization of the strain pattern after CRT agreed with clinical outcome for the three cases.

Original languageEnglish
Title of host publicationMICCAI 2010
Subtitle of host publicationMedical Image Computing and Computer-Assisted Intervention – MICCAI 2010
Pages1-8
Number of pages8
EditionPART 2
DOIs
Publication statusPublished - 2010
Event13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010 - Beijing, China
Duration: 20 Sept 201024 Sept 2010

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 2
Volume6362 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010
Country/TerritoryChina
CityBeijing
Period20/09/1024/09/10

Fingerprint

Dive into the research topics of 'Temporal diffeomorphic free-form deformation for strain quantification in 3D-US images'. Together they form a unique fingerprint.

Cite this