The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services.

D Gareth Evans; Julian Barwell; Diana M Eccles; Amanda Collins; Louise Izatt; Chris Jacobs; Alan Donaldson; Angela F Brady; Andrew Cuthbert; Rachel Harrison; Sue Thomas; Anthony Howell; Zosia Miedzybrodzka; Alex Murray; Lynda Luke; Lesley Smart; Vian Salih; Ilyena Froud; Nicky Turner; Natarajan Vaithilingam; Tracey Hales; Samantha Bennion; Celia Diver-Hall; Jackie McGee; RDouglas MacMillan; Nicky Scott; Diana Dalgleish; Alison Smith; Celia Lewis; Janet Self; GeraldP Gui; DMark Sibbering; Samantha Crockett; Simerjit Rai; Harriet Goddard; Lorraine Roberts; Jayne Beesley; GarethS Goddard; Adam Shaw; AndrewJ Wallace

doi:10.1186/s13058-014-0442-6

The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services.

D Gareth Evans, Julian Barwell, Diana M Eccles, Amanda Collins, Louise Izatt, Chris Jacobs, Alan Donaldson, Angela F Brady, Andrew Cuthbert, Rachel Harrison, Sue Thomas, Anthony Howell, Zosia Miedzybrodzka, Alex Murray, Lynda Luke (Collaborator), Lesley Smart (Collaborator), Vian Salih (Collaborator), Ilyena Froud (Collaborator), Nicky Turner (Collaborator), Natarajan Vaithilingam (Collaborator)Tracey Hales (Collaborator), Samantha Bennion (Collaborator), Celia Diver-Hall (Collaborator), Jackie McGee (Collaborator), RDouglas MacMillan (Collaborator), Nicky Scott (Collaborator), Diana Dalgleish (Collaborator), Alison Smith (Collaborator), Celia Lewis (Collaborator), Janet Self (Collaborator), GeraldP Gui (Collaborator), DMark Sibbering (Collaborator), Samantha Crockett (Collaborator), Simerjit Rai (Collaborator), Harriet Goddard (Collaborator), Lorraine Roberts (Collaborator), Jayne Beesley (Collaborator), GarethS Goddard (Collaborator), Adam Shaw (Collaborator), AndrewJ Wallace (Collaborator)

Division of Cancer Sciences (L5)

Research output: Contribution to journal › Article › peer-review

Abstract

INTRODUCTION: It is frequent for news items to lead to a short lived temporary increase in interest in a particular health related service, however it is rare for this to have a long lasting effect. In 2013, in the UK in particular, there has been unprecedented publicity in hereditary breast cancer, with Angelina Jolie's decision to have genetic testing for the BRCA1 gene and subsequently undergo risk reducing mastectomy (RRM), and a pre-release of the NICE guidelines on familial breast cancer in January and their final release on 26th June. The release of NICE guidelines created a lot of publicity over the potential for use of chemoprevention using tamoxifen or raloxifene. However, the longest lasting news story was the release of details of film actress Angelina Jolie's genetic test and surgery. METHODS: To assess the potential effects of the 'Angelina Jolie' effect, referral data specific to breast cancer family history was obtained from around the UK for the years 2012 and 2013. A consortium of over 30 breast cancer family history clinics that have contributed to two research studies on early breast surveillance were asked to participate as well as 10 genetics centres. Monthly referrals to each service were collated and increases from 2012 to 2013 assessed. RESULTS: Data from 12 family history clinics and 9 regional genetics services showed a rise in referrals from May 2013 onwards. Referrals were nearly 2.5 fold in June and July 2013 from 1,981 (2012) to 4,847 (2013) and remained at around two-fold to October 2013. Demand for BRCA1/2 testing almost doubled and there were also many more enquiries for risk reducing mastectomy. Internal review shows that there was no increase in inappropriate referrals. CONCLUSIONS: The Angelina Jolie effect has been long lasting and global, and appears to have increased referrals to centres appropriately.

Original language	English
Pages (from-to)	16 - 442
Journal	Breast Cancer Research (Print)
Volume	16
Issue number	5
DOIs	https://doi.org/10.1186/s13058-014-0442-6
Publication status	Published - 2014

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Evans, D. G., Barwell, J., Eccles, D. M., Collins, A., Izatt, L., Jacobs, C., Donaldson, A., Brady, A. F., Cuthbert, A., Harrison, R., Thomas, S., Howell, A., Miedzybrodzka, Z., Murray, A., Luke, L., Smart, L., Salih, V., Froud, I., Turner, N., ... Wallace, A. (2014). The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services. Breast Cancer Research (Print), 16(5), 16 - 442. https://doi.org/10.1186/s13058-014-0442-6

@article{53b09bfd45df446193aaefc8d7a86423,

title = "The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services.",

abstract = "INTRODUCTION: It is frequent for news items to lead to a short lived temporary increase in interest in a particular health related service, however it is rare for this to have a long lasting effect. In 2013, in the UK in particular, there has been unprecedented publicity in hereditary breast cancer, with Angelina Jolie's decision to have genetic testing for the BRCA1 gene and subsequently undergo risk reducing mastectomy (RRM), and a pre-release of the NICE guidelines on familial breast cancer in January and their final release on 26th June. The release of NICE guidelines created a lot of publicity over the potential for use of chemoprevention using tamoxifen or raloxifene. However, the longest lasting news story was the release of details of film actress Angelina Jolie's genetic test and surgery. METHODS: To assess the potential effects of the 'Angelina Jolie' effect, referral data specific to breast cancer family history was obtained from around the UK for the years 2012 and 2013. A consortium of over 30 breast cancer family history clinics that have contributed to two research studies on early breast surveillance were asked to participate as well as 10 genetics centres. Monthly referrals to each service were collated and increases from 2012 to 2013 assessed. RESULTS: Data from 12 family history clinics and 9 regional genetics services showed a rise in referrals from May 2013 onwards. Referrals were nearly 2.5 fold in June and July 2013 from 1,981 (2012) to 4,847 (2013) and remained at around two-fold to October 2013. Demand for BRCA1/2 testing almost doubled and there were also many more enquiries for risk reducing mastectomy. Internal review shows that there was no increase in inappropriate referrals. CONCLUSIONS: The Angelina Jolie effect has been long lasting and global, and appears to have increased referrals to centres appropriately.",

author = "Evans, {D Gareth} and Julian Barwell and Eccles, {Diana M} and Amanda Collins and Louise Izatt and Chris Jacobs and Alan Donaldson and Brady, {Angela F} and Andrew Cuthbert and Rachel Harrison and Sue Thomas and Anthony Howell and Zosia Miedzybrodzka and Alex Murray and Lynda Luke and Lesley Smart and Vian Salih and Ilyena Froud and Nicky Turner and Natarajan Vaithilingam and Tracey Hales and Samantha Bennion and Celia Diver-Hall and Jackie McGee and RDouglas MacMillan and Nicky Scott and Diana Dalgleish and Alison Smith and Celia Lewis and Janet Self and GeraldP Gui and DMark Sibbering and Samantha Crockett and Simerjit Rai and Harriet Goddard and Lorraine Roberts and Jayne Beesley and GarethS Goddard and Adam Shaw and AndrewJ Wallace",

year = "2014",

doi = "10.1186/s13058-014-0442-6",

language = "English",

volume = "16",

pages = "16 -- 442",

journal = "Breast Cancer Research (Print)",

issn = "1465-5411",

publisher = "Springer Nature",

number = "5",

}

Evans, DG, Barwell, J, Eccles, DM, Collins, A, Izatt, L, Jacobs, C, Donaldson, A, Brady, AF, Cuthbert, A, Harrison, R, Thomas, S, Howell, A, Miedzybrodzka, Z, Murray, A, Luke, L, Smart, L, Salih, V, Froud, I, Turner, N, Vaithilingam, N, Hales, T, Bennion, S, Diver-Hall, C, McGee, J, MacMillan, RD, Scott, N, Dalgleish, D, Smith, A, Lewis, C, Self, J, Gui, G, Sibbering, DM, Crockett, S, Rai, S, Goddard, H, Roberts, L, Beesley, J, Goddard, G, Shaw, A & Wallace, A 2014, 'The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services.', Breast Cancer Research (Print), vol. 16, no. 5, pp. 16 - 442. https://doi.org/10.1186/s13058-014-0442-6

TY - JOUR

T1 - The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services.

AU - Evans, D Gareth

AU - Barwell, Julian

AU - Eccles, Diana M

AU - Collins, Amanda

AU - Izatt, Louise

AU - Jacobs, Chris

AU - Donaldson, Alan

AU - Brady, Angela F

AU - Cuthbert, Andrew

AU - Harrison, Rachel

AU - Thomas, Sue

AU - Howell, Anthony

AU - Miedzybrodzka, Zosia

AU - Murray, Alex

A2 - Luke, Lynda

A2 - Smart, Lesley

A2 - Salih, Vian

A2 - Froud, Ilyena

A2 - Turner, Nicky

A2 - Vaithilingam, Natarajan

A2 - Hales, Tracey

A2 - Bennion, Samantha

A2 - Diver-Hall, Celia

A2 - McGee, Jackie

A2 - MacMillan, RDouglas

A2 - Scott, Nicky

A2 - Dalgleish, Diana

A2 - Smith, Alison

A2 - Lewis, Celia

A2 - Self, Janet

A2 - Gui, GeraldP

A2 - Sibbering, DMark

A2 - Crockett, Samantha

A2 - Rai, Simerjit

A2 - Goddard, Harriet

A2 - Roberts, Lorraine

A2 - Beesley, Jayne

A2 - Goddard, GarethS

A2 - Shaw, Adam

A2 - Wallace, AndrewJ

PY - 2014

Y1 - 2014

N2 - INTRODUCTION: It is frequent for news items to lead to a short lived temporary increase in interest in a particular health related service, however it is rare for this to have a long lasting effect. In 2013, in the UK in particular, there has been unprecedented publicity in hereditary breast cancer, with Angelina Jolie's decision to have genetic testing for the BRCA1 gene and subsequently undergo risk reducing mastectomy (RRM), and a pre-release of the NICE guidelines on familial breast cancer in January and their final release on 26th June. The release of NICE guidelines created a lot of publicity over the potential for use of chemoprevention using tamoxifen or raloxifene. However, the longest lasting news story was the release of details of film actress Angelina Jolie's genetic test and surgery. METHODS: To assess the potential effects of the 'Angelina Jolie' effect, referral data specific to breast cancer family history was obtained from around the UK for the years 2012 and 2013. A consortium of over 30 breast cancer family history clinics that have contributed to two research studies on early breast surveillance were asked to participate as well as 10 genetics centres. Monthly referrals to each service were collated and increases from 2012 to 2013 assessed. RESULTS: Data from 12 family history clinics and 9 regional genetics services showed a rise in referrals from May 2013 onwards. Referrals were nearly 2.5 fold in June and July 2013 from 1,981 (2012) to 4,847 (2013) and remained at around two-fold to October 2013. Demand for BRCA1/2 testing almost doubled and there were also many more enquiries for risk reducing mastectomy. Internal review shows that there was no increase in inappropriate referrals. CONCLUSIONS: The Angelina Jolie effect has been long lasting and global, and appears to have increased referrals to centres appropriately.

AB - INTRODUCTION: It is frequent for news items to lead to a short lived temporary increase in interest in a particular health related service, however it is rare for this to have a long lasting effect. In 2013, in the UK in particular, there has been unprecedented publicity in hereditary breast cancer, with Angelina Jolie's decision to have genetic testing for the BRCA1 gene and subsequently undergo risk reducing mastectomy (RRM), and a pre-release of the NICE guidelines on familial breast cancer in January and their final release on 26th June. The release of NICE guidelines created a lot of publicity over the potential for use of chemoprevention using tamoxifen or raloxifene. However, the longest lasting news story was the release of details of film actress Angelina Jolie's genetic test and surgery. METHODS: To assess the potential effects of the 'Angelina Jolie' effect, referral data specific to breast cancer family history was obtained from around the UK for the years 2012 and 2013. A consortium of over 30 breast cancer family history clinics that have contributed to two research studies on early breast surveillance were asked to participate as well as 10 genetics centres. Monthly referrals to each service were collated and increases from 2012 to 2013 assessed. RESULTS: Data from 12 family history clinics and 9 regional genetics services showed a rise in referrals from May 2013 onwards. Referrals were nearly 2.5 fold in June and July 2013 from 1,981 (2012) to 4,847 (2013) and remained at around two-fold to October 2013. Demand for BRCA1/2 testing almost doubled and there were also many more enquiries for risk reducing mastectomy. Internal review shows that there was no increase in inappropriate referrals. CONCLUSIONS: The Angelina Jolie effect has been long lasting and global, and appears to have increased referrals to centres appropriately.

UR - https://www.altmetric.com/details/2696513

U2 - 10.1186/s13058-014-0442-6

DO - 10.1186/s13058-014-0442-6

M3 - Article

C2 - 25510853

SN - 1465-5411

VL - 16

SP - 16

EP - 442

JO - Breast Cancer Research (Print)

JF - Breast Cancer Research (Print)

IS - 5

ER -

The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services.

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