The birth and postnatal development of purinergic signalling

G. Burnstock; B. B. Fredholm; R. A. North; A. Verkhratsky

doi:10.1111/j.1748-1716.2010.02114.x

The birth and postnatal development of purinergic signalling

G. Burnstock, B. B. Fredholm, R. A. North, A. Verkhratsky

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Abstract

The purinergic signalling system is one of the most ancient and arguably the most widespread intercellular signalling system in living tissues. In this review we present a detailed account of the early developments and current status of purinergic signalling. We summarize the current knowledge on purinoceptors, their distribution and role in signal transduction in various tissues in physiological and pathophysiological conditions. © 2010 Scandinavian Physiological Society.

Original language	English
Pages (from-to)	93-147
Number of pages	54
Journal	Acta Physiologica
Volume	199
Issue number	2
DOIs	https://doi.org/10.1111/j.1748-1716.2010.02114.x
Publication status	Published - Jun 2010

Keywords

Adenosine
ATP
Co-transmission
History
Purinergic signalling
Purinoceptors

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10.1111/j.1748-1716.2010.02114.x

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KW - Adenosine

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KW - Co-transmission

KW - History

KW - Purinergic signalling

KW - Purinoceptors

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The birth and postnatal development of purinergic signalling

Abstract

Keywords

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