The C. elegans genome sequencing project: A beginning

J. Sulston, Z. Du, K. Thomas, R. Wilson, L. Hillier, R. Staden, N. Halloran, P. Green, J. Thierry-Mieg, L. Qiu, S. Dear, A. Coulson, M. Craxton, R. Durbin, M. Berks, M. Metzstein, T. Hawkins, R. Ainscough, R. Waterston

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The long-term goal of this project is the elucidation of the complete sequence of the Caenorhabditis elegans genome. During the first year methods have been developed and a strategy implemented that is amenable to large-scale sequencing. The three cosmids sequenced in this initial phase are surprisingly rich in genes, many of which have mammalian homologues.
    Original languageEnglish
    Pages (from-to)37-41
    Number of pages4
    JournalNature
    Volume356
    Issue number6364
    DOIs
    Publication statusPublished - 5 Mar 1992

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