The Challenges Faced in Developing Novel Drug Radiation Combinations in Non-small Cell Lung Cancer

S. Harrow*, G. G. Hanna, C. Faivre-Finn, F. McDonald, A. J. Chalmers

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

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Abstract

Lung cancer is the most common cancer diagnosed in the UK. Outcomes for patients with this disease remain poor and new strategies to treat this disease require investigation. One potential option is to combine novel agents with radiotherapy in clinical studies. Here we discuss some of the important issues to consider when combining novel agents with radiotherapy, together with potential solutions as discussed at a recent Clinical Translational Radiotherapy Group (CTRad) workshop.

Original languageEnglish
Pages (from-to)720-725
Number of pages6
JournalClinical Oncology
Volume28
Issue number11
Early online date31 Aug 2016
DOIs
Publication statusPublished - 1 Nov 2016

Keywords

  • DNA damage repair
  • immunotherapy
  • NSCLC
  • radiotherapy
  • umbrella study

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