The complete amino acid sequence of the human erythrocyte membrane anion-transport protein deduced from the cDNA sequence

M. J A Tanner, P. G. Martin, S. High

Research output: Contribution to journalArticlepeer-review

Abstract

We have isolated cDNA clones corresponding to the red cell membrane anion-transport protein. The cDNA clones cover 3475 bases of the mRNA and contain the entire protein-coding region, 150 bases of the 5' untranslated region and part of the 3' non-coding region, but do not extend to the 3' end of the mRNA. The translated protein sequence predicts that the human red cell anion transporter contains 911 amino acids. The availability of the amino acid sequence allows the interpretation of some of the many studies on the chemical and proteolytic modification of the human protein aimed at examining the structure and mechanism of this membrane transport protein.
Original languageEnglish
Pages (from-to)703-712
Number of pages9
JournalBiochemical Journal
Volume256
Issue number3
Publication statusPublished - 1988

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